ID A0A1Y0G9G9_9PROT Unreviewed; 336 AA.
AC A0A1Y0G9G9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=CAP31_11640 {ECO:0000313|EMBL:ARU32268.1};
OS Sulfuriferula sp. AH1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Sulfuricellaceae; Sulfuriferula.
OX NCBI_TaxID=1985873 {ECO:0000313|EMBL:ARU32268.1, ECO:0000313|Proteomes:UP000195558};
RN [1] {ECO:0000313|EMBL:ARU32268.1, ECO:0000313|Proteomes:UP000195558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AH1 {ECO:0000313|EMBL:ARU32268.1,
RC ECO:0000313|Proteomes:UP000195558};
RA Jones D.S., Hua A.A., Roepke E.W., Bailey J.V.;
RT "The complete genome sequence of Sulfuriferula sp. str. AH1, a sulfur-
RT oxidizing autotroph isolated from weathered sulfide-bearing rock from the
RT Duluth Complex.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
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DR EMBL; CP021138; ARU32268.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y0G9G9; -.
DR KEGG; sulf:CAP31_11640; -.
DR OrthoDB; 9770982at2; -.
DR Proteomes; UP000195558; Chromosome.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000195558}.
FT DOMAIN 20..189
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 214..329
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 336 AA; 37682 MW; DF976C53CD2C7698 CRC64;
MRIKPEQLAS HLAKDLKPLY CVYGDEPLLV LEAADQIRQA AREQGYSERE IYQIEGRFNW
QTLLDSGNNL SLFSSRRLVD MRIPSGKPGI DGGKALQSYC AALPADSVTL ITLPKLDRQA
TAAKWFTALD NAGATIAVYP VSNEQLPRWI GERLAQQKQQ ADSDTLRFLT QKVEGNLLAA
QQEIRKLALL FPAGRLDFAS VREAVLDVAR YDVFKLADAL LLSDVPRLMR MLDGLRNEGE
APTLILWTIT RELRILTRLK TAQNSGIAPA RLMRDVGVWE SRQTMVEKAL QRVKLDTLTH
CLRQAAAIDR MIKGLVNEDP WDALKQLALS IALPQR
//
