ID A0A1Y0H152_9BACT Unreviewed; 459 AA.
AC A0A1Y0H152;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Magnesium transporter MgtE {ECO:0000256|RuleBase:RU362011};
GN ORFNames=CCB80_06835 {ECO:0000313|EMBL:ARU40875.1};
OS Armatimonadetes bacterium Uphvl-Ar1.
OC Bacteria; Armatimonadota.
OX NCBI_TaxID=2004467 {ECO:0000313|EMBL:ARU40875.1, ECO:0000313|Proteomes:UP000196284};
RN [1] {ECO:0000313|EMBL:ARU40875.1, ECO:0000313|Proteomes:UP000196284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Uphvl-Ar1 {ECO:0000313|EMBL:ARU40875.1,
RC ECO:0000313|Proteomes:UP000196284};
RA Woodhouse J.N., Makower A.K., Ionescu D., Grossart H.-P., Neilan B.A.,
RA Dittmann E.;
RT "Draft genome sequences of three Uncultured Armatimonadetes, binned from a
RT Microcystis sp. enrichment culture and from Microcystis bloom
RT metagenomes.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a magnesium transporter.
CC {ECO:0000256|RuleBase:RU362011}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU362011}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362011};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362011}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749, ECO:0000256|RuleBase:RU362011}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362011}.
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DR EMBL; CP021423; ARU40875.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y0H152; -.
DR OrthoDB; 9790355at2; -.
DR Proteomes; UP000196284; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04606; CBS_pair_Mg_transporter; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.25.60.10; MgtE N-terminal domain-like; 1.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR006668; Mg_transptr_MgtE_intracell_dom.
DR InterPro; IPR038076; MgtE_N_sf.
DR InterPro; IPR006669; MgtE_transporter.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR NCBIfam; TIGR00400; mgtE; 1.
DR PANTHER; PTHR43773; MAGNESIUM TRANSPORTER MGTE; 1.
DR PANTHER; PTHR43773:SF1; MAGNESIUM TRANSPORTER MGTE; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01769; MgtE; 1.
DR Pfam; PF03448; MgtE_N; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM00924; MgtE_N; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 1.
DR SUPFAM; SSF158791; MgtE N-terminal domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cell membrane {ECO:0000256|RuleBase:RU362011};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|RuleBase:RU362011};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362011};
KW Metal-binding {ECO:0000256|RuleBase:RU362011};
KW Reference proteome {ECO:0000313|Proteomes:UP000196284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362011};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362011};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362011}.
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 395..419
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT DOMAIN 145..208
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 210..266
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 459 AA; 50154 MW; D50200599BBBF569 CRC64;
MPRLLPTIQE RLLRLKGLLS HLGTARGADR VKAELSGQRA EDLAEGMARM EPEDAAALLQ
AMDPIQAGNV MVELPTDTAR EIVDELSDEV LASYLDALPM DDAIDLAEEV GEERFESLLE
VIPAEDAAEI RRLMAYPEES VGRLMTERYF WAKPDMTIKQ ILADLRKAGE EKYEQVNDIY
VVDDAHHLLG VTSLRRVLRV PQSTEVAEIM RVDPVTVHAT DDEENAARTM ARYGFYALPV
LDEAGRLVGI FTGDDAQTIL REAETEDVLA VGGVTGDAEP YYALNPWSLY KRRFPWLIAL
FVAETLTGAV MRHYGQDTEV GVPPLMFFLP LILGAGGNSG AQVTTTITRA LALDEVKTGD
WLAVMGKEFV VALMIGASLG LLGFARAFFG WSTGMGLSLV VGLALPIVVL WATTIGSILP
IGAKRLGFDP AVMSAPFITT FVDATGLIIY FEIARRLLG
//
