ID   A0A1Y0HB63_9BACT        Unreviewed;       517 AA.
AC   A0A1Y0HB63;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=CCB81_11355 {ECO:0000313|EMBL:ARU44704.1};
OS   Armatimonadetes bacterium Uphvl-Ar2.
OC   Bacteria; Armatimonadota.
OX   NCBI_TaxID=2004468 {ECO:0000313|EMBL:ARU44704.1, ECO:0000313|Proteomes:UP000195582};
RN   [1] {ECO:0000313|EMBL:ARU44704.1, ECO:0000313|Proteomes:UP000195582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Uphvl-Ar2 {ECO:0000313|EMBL:ARU44704.1,
RC   ECO:0000313|Proteomes:UP000195582};
RA   Woodhouse J.N., Makower A.K., Ionescu D., Grossart H.-P., Neilan B.A.,
RA   Dittmann E.;
RT   "Draft genome sequences of three Uncultured Armatimonadetes, binned from a
RT   Microcystis sp. enrichment culture and from Microcystis bloom
RT   metagenomes.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP021424; ARU44704.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y0HB63; -.
DR   OrthoDB; 8196020at2; -.
DR   Proteomes; UP000195582; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195582};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        31..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        222..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          346..463
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   517 AA;  56178 MW;  3A892611FB3BD3EC CRC64;
     MKFGARFLKV SRSVPRMPLP EERKQREQRS VSGYIAFLSI IYLLNVFIPD GSLATMLFLL
     ANGVGLLGQV VLSALSRSLR VTASIALIQG IFVAVSFLPG RALSAAVITG AVSTGIVVGT
     LFFVAGTVGA TLMGLADMQR WESRRKRMSR HQRIGVLLDL KDRISVASLR GEPDAQSNWT
     DKIGRNLFGW AFGLGFGLDV SFVIIASLLL RTGYAMSSLN EPTVAIVFLY SLSFLGIFGA
     NLLIGYCSGR FPRMLAATVL LTASGSSFMI WPGHPTYQLA QFGMNRDMFW QGVGISMLIS
     TVGWLAAYVQ RKTERIWKLQ RGDASVLNEE IQRLENSLLR DQSRKCVVAV DVVGSTRMKA
     NADMLVSEWC FREYQQIVTQ CVEDEGGQVV NTAGDGVVAS FEDPACALEA AAAVRDRLLV
     FNARGNRLSE PFQVRIGIDS AEVQGNLAEV QFSQLIDTAA HIEAMTPAGA IGVSQSFMAL
     LPSERATQHG NSADGKPIFL MRESGSALWA EPLPTSS
//