ID A0A1Y0I648_9GAMM Unreviewed; 189 AA.
AC A0A1Y0I648;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Lipopolysaccharide export system protein LptA {ECO:0000256|HAMAP-Rule:MF_01914};
DE Flags: Precursor;
GN Name=lptA {ECO:0000256|HAMAP-Rule:MF_01914,
GN ECO:0000313|EMBL:ARU55968.1};
GN ORFNames=OLMES_1894 {ECO:0000313|EMBL:ARU55968.1};
OS Oleiphilus messinensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oleiphilaceae; Oleiphilus.
OX NCBI_TaxID=141451 {ECO:0000313|EMBL:ARU55968.1, ECO:0000313|Proteomes:UP000196027};
RN [1] {ECO:0000313|EMBL:ARU55968.1, ECO:0000313|Proteomes:UP000196027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ME102 {ECO:0000313|EMBL:ARU55968.1,
RC ECO:0000313|Proteomes:UP000196027};
RA Kozyavkin S.A., Slesarev A.I., Golyshin P.N., Korzhenkov A.,
RA Golyshina O.N., Toshchakov S.V.;
RT "Genomic insights into alkan degradation activity of Oleiphilus
RT messinensis.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS).
CC Required for the translocation of LPS from the inner membrane to the
CC outer membrane. May form a bridge between the inner membrane and the
CC outer membrane, via interactions with LptC and LptD, thereby
CC facilitating LPS transfer across the periplasm. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SIMILARITY: Belongs to the LptA family. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
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DR EMBL; CP021425; ARU55968.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y0I648; -.
DR KEGG; ome:OLMES_1894; -.
DR OrthoDB; 9795964at2; -.
DR Proteomes; UP000196027; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0001530; F:lipopolysaccharide binding; IEA:InterPro.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01914; LPS_assembly_LptA; 1.
DR InterPro; IPR014340; LptA.
DR InterPro; IPR005653; OstA-like_N.
DR NCBIfam; TIGR03002; outer_YhbN_LptA; 1.
DR PANTHER; PTHR36504; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR PANTHER; PTHR36504:SF1; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_01914};
KW Reference proteome {ECO:0000313|Proteomes:UP000196027};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_01914};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01914}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01914"
FT CHAIN 24..189
FT /note="Lipopolysaccharide export system protein LptA"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01914"
FT /id="PRO_5013406083"
FT DOMAIN 34..140
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT REGION 149..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 189 AA; 20705 MW; CB535EB118739588 CRC64;
MHRFQPLISC LCIMMLGAPA ALALTAGSDD PIRIEANQAS LDDSKGIATY VGRVVVTQGP
SKLEADRVVI FTENNQLVRI EAHGDPAHFT QLDTAKAQQT DAYGDQIIYE QREELLKLLH
NAKLQQGKNS FQGDMIEYDT INRIVNAKGS EAGDGKNTRV ELIIHPQSRE TSADQKSAQP
TDSEDSAQN
//
