ID A0A1Y0MCF5_9FLAO Unreviewed; 278 AA.
AC A0A1Y0MCF5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=BTO04_04160 {ECO:0000313|EMBL:ARV07982.1};
OS Polaribacter sp. SA4-10.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=754397 {ECO:0000313|EMBL:ARV07982.1, ECO:0000313|Proteomes:UP000195822};
RN [1] {ECO:0000313|EMBL:ARV07982.1, ECO:0000313|Proteomes:UP000195822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA4-10 {ECO:0000313|EMBL:ARV07982.1,
RC ECO:0000313|Proteomes:UP000195822};
RA Kumagai Y., Yoshizawa S., Kogure K., Iwasaki W.;
RT "Trade-off between light-utilization and light-protection in marine
RT flavobacteria.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP019331; ARV07982.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y0MCF5; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000195822; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0036524; F:protein deglycase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR InterPro; IPR017283; HchA.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR PIRSF; PIRSF037798; Chaperone_HchA; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000195822};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 68..266
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 278 AA; 30525 MW; 2081B54D2C2CBD1B CRC64;
MAQPKLEADG SYSPSSLALS LGTVSKTDFE DIKYTKYQGD KSKILVIFTE KKNLEMKNGK
FFSTGNHPIE ALVPMLHLKN AGFDFEIATP TGKPVVFEMW AFPEEDANVK AIYNEYKSSF
EQPKKLADFI TNSFVNDSSY AAVFVPGGHG AMIGIPEDRN VGKVLNWAYQ SDLFTITLCH
GPGALLSTTL DNQKFIYDGY KMAVFPDAVD EMTPMIGYLP GHMKNGVSER LKKLGATIVN
TESDKTVCVD RKLITGASPL ASNELGKLAA NTLLKELK
//
