ID A0A1Y0N980_9BURK Unreviewed; 850 AA.
AC A0A1Y0N980;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=phoR_1 {ECO:0000313|EMBL:ARV18370.1};
GN ORFNames=AEP_01422 {ECO:0000313|EMBL:ARV18370.1};
OS Curvibacter sp. AEP1-3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Curvibacter.
OX NCBI_TaxID=1844971 {ECO:0000313|EMBL:ARV18370.1, ECO:0000313|Proteomes:UP000196261};
RN [1] {ECO:0000313|EMBL:ARV18370.1, ECO:0000313|Proteomes:UP000196261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AEP1-3 {ECO:0000313|EMBL:ARV18370.1,
RC ECO:0000313|Proteomes:UP000196261};
RA Foret S., Pietschke C., Fraune S.;
RT "Curvibacter sp. AEP1.3.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP015698; ARV18370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y0N980; -.
DR OrthoDB; 9810730at2; -.
DR Proteomes; UP000196261; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000196261};
KW Transferase {ECO:0000313|EMBL:ARV18370.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 252..298
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 376..426
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 450..504
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 632..849
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 850 AA; 94245 MW; 0E2AF45A23563F1D CRC64;
MSHTEWLPGV RRHLAAPFSI STIIMGATLA VMVLLTVVYS AYTYHRIAGE TLRVAQTNAT
SVARMVAGSS SAALIAERLN TLQANAIDAV QLPGIDRISI YKPDGVNLME VTRARDGVHV
DTGKHLGASL VASGLPEGGL ESDHFVAWQE VDKENTLNNV WVRVDYSLED RDAELQRLWL
QSFWMALILT GVVMLCLHII IRKALAPVRE LTEFAAQIPL RMGDEVNLPK ASVEVGQLQA
AINQASRGMA LQVNRVQAIV NTAAEAIIGL DEFGRVTTTN PAASSMFGRS EDELLGQTIE
CCVPGLNEQA LHEMFGQGME HILSISRVTR HDFMGTRADG TLFPVEICLG EVKNDKTLRY
ACIVRDLTDE RAAQETSELY ERALASSHNA VFITNGKMEH QPIVYINDAF QKFVNLPRWD
ILGESLALLR GKNADDPGVR ELTLAVREHR NANVTIHREL ENGEVQIAEV SLSPVMSDKG
TLTHFVGIVS DITARVRAEE AMAERRAQLD AIFSLSPDGF VMFDAHDQLV FANPAFERMT
GLGKHASTPV SLSQFEQQLL SLCDESQALP TMRGDQPDAS WEEKLQLARP QRRVVQARSR
RNEAGRRETI LYFRDVTHED QVDRMKSEFL TAAAHELRTP MVSIFGFSEL LTRRKFTPER
QTDMLQTIHR QSGLLVKMLN ELLDLARIES RGGLDMQINA HPLDETVQYC IKGLMLKDTD
RPVLHDTLPS LQVLMDPEKM QQALTNLLAN AFKYSPQGGD VSLSVRTEED EGGRYAVIDV
RDQGIGMTPE QLERAFERFY RADASGNIPG TGLGLSLVKE IAELHKGRVT LQSTFGEGTT
ASLWIPLAEA
//
