ID A0A1Y1CDP9_9BACT Unreviewed; 479 AA.
AC A0A1Y1CDP9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Iduronate-2-sulfatase {ECO:0000313|EMBL:BAX78440.1};
GN ORFNames=ALGA_0045 {ECO:0000313|EMBL:BAX78440.1};
OS Labilibaculum antarcticum.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinifilaceae;
OC Labilibaculum.
OX NCBI_TaxID=1717717 {ECO:0000313|EMBL:BAX78440.1, ECO:0000313|Proteomes:UP000218267};
RN [1] {ECO:0000313|Proteomes:UP000218267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPP2 {ECO:0000313|Proteomes:UP000218267};
RA Watanabe M., Kojima H., Fukui M.;
RT "Complete genome sequence of Marinifilaceae bacterium strain SPP2, isolated
RT from the Antarctic marine sediment.";
RL Mar. Genomics 0:0-0(2017).
RN [2] {ECO:0000313|EMBL:BAX78440.1, ECO:0000313|Proteomes:UP000218267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPP2 {ECO:0000313|EMBL:BAX78440.1,
RC ECO:0000313|Proteomes:UP000218267};
RA Watanabe M., Kojima H., Fukui M.;
RT "Complete genome sequence of Marinifilaceae bacterium strain SPP2, isolated
RT from the Antarctic marine sediment.";
RL Mar. Genomics 39:1-2(2018).
RN [3] {ECO:0000313|Proteomes:UP000218267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPP2 {ECO:0000313|Proteomes:UP000218267};
RA Watanabe M., Kojima H., Fukui M.;
RT "Labilibaculum antarcticum sp. nov., a novel facultative anaerobic,
RT psychrotorelant bacterium isolated from marine sediment of Antarctica.";
RL Antonie Van Leeuwenhoek 113:349-355(2020).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP018042; BAX78440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1CDP9; -.
DR KEGG; mbas:ALGA_0045; -.
DR Proteomes; UP000218267; Chromosome.
DR GO; GO:0004423; F:iduronate-2-sulfatase activity; IEA:InterPro.
DR CDD; cd16030; iduronate-2-sulfatase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR035874; IDS.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR45953; IDURONATE 2-SULFATASE; 1.
DR PANTHER; PTHR45953:SF1; IDURONATE 2-SULFATASE; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..479
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012056009"
FT DOMAIN 34..394
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 479 AA; 53835 MW; 8C1E91EB6DC162A5 CRC64;
MKTIKMKNKH ILFALFFCAL LFFQCSKPSK EGKQNVLLIC IDDLRPELKC FGAEYISSPN
IDRLAANGVS FQKHFVNAPS CGPSRYTLLT GQYGPANNNA LFLRANKIAK GIETIHPSMP
EWFKTHGYAT VSVGKVSHHP GGRGGSDWND STIIEVPKAW DKHLMPIAEW EHPRGMMHGL
AHGEVRIKAG DMDVFQTVEG DDNIYPDGAI TNEALKQLRV LSTDEEKPFF LAVGIIKPHL
PFGAPKSYFD LYEGVKFPSI EHPQKPEGKT TWHSSGEFMN YNRWGKDPNK DMAFADEVRR
HYAACVSYAD AQVGKILEEL KRTGADKNTI VVLWGDHGWH LGEHAIWGKH SLFEESLHSP
MIIYYPGMKH EGYKTNAIVE TLDIFPTLCD LTGVEIPEFV QGVSLKEILE YPNTTGHSAV
AYTNEASTIR TATHRMTLHK DGFVELYDHT TSENETKNVA DKHLELVKEL KNELAAKMQ
//
