ID A0A1Y1CEZ6_9BACT Unreviewed; 1087 AA.
AC A0A1Y1CEZ6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=ALGA_0536 {ECO:0000313|EMBL:BAX78929.1};
OS Labilibaculum antarcticum.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinifilaceae;
OC Labilibaculum.
OX NCBI_TaxID=1717717 {ECO:0000313|EMBL:BAX78929.1, ECO:0000313|Proteomes:UP000218267};
RN [1] {ECO:0000313|Proteomes:UP000218267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPP2 {ECO:0000313|Proteomes:UP000218267};
RA Watanabe M., Kojima H., Fukui M.;
RT "Complete genome sequence of Marinifilaceae bacterium strain SPP2, isolated
RT from the Antarctic marine sediment.";
RL Mar. Genomics 0:0-0(2017).
RN [2] {ECO:0000313|EMBL:BAX78929.1, ECO:0000313|Proteomes:UP000218267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPP2 {ECO:0000313|EMBL:BAX78929.1,
RC ECO:0000313|Proteomes:UP000218267};
RA Watanabe M., Kojima H., Fukui M.;
RT "Complete genome sequence of Marinifilaceae bacterium strain SPP2, isolated
RT from the Antarctic marine sediment.";
RL Mar. Genomics 39:1-2(2018).
RN [3] {ECO:0000313|Proteomes:UP000218267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPP2 {ECO:0000313|Proteomes:UP000218267};
RA Watanabe M., Kojima H., Fukui M.;
RT "Labilibaculum antarcticum sp. nov., a novel facultative anaerobic,
RT psychrotorelant bacterium isolated from marine sediment of Antarctica.";
RL Antonie Van Leeuwenhoek 113:349-355(2020).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; AP018042; BAX78929.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1CEZ6; -.
DR KEGG; mbas:ALGA_0536; -.
DR Proteomes; UP000218267; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.3170.10; Recbcd, chain B, domain 2; 1.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 1..463
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 502..759
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 9..16
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1087 AA; 125103 MW; A9C675343A0C7711 CRC64;
MSELSIYRAS AGSGKTYTLT KEYLNLVFED PLNYKSILAV TFTNKATDEM KSRIVKEIYL
LSQSDDSPYA KELCEKHNLN SKELILRAKE ILNRLLHDYS RFSVTTIDSF FQKVVRSFTR
EIGLQMGYNI ELDQRRVLNE VADLLFNDVD KDPQLRSWLT DFAESKIREG KNWNFKQEIL
EVGNEVFKED FKNFSDKLID KLADKKFLSS YRKTLKEIKD EFETFFNKVG EETRGILAQH
GLDVTEFAYG KSGVAGYLSG LGNGGKMDPG IRARSAVDTP EKWTTGKAST STKQAVGEAC
SAGLNDLLKK AVNHYDEQSM LYKSTDKTLS YIYTLGILTD LSKKVQQYSE SENIFLLSDA
SRLLRSIIGD NDTPFIYEKI GNVYKHFMID EFQDTSSMQW ESFRPLVTNS LAEDKHSLVV
GDVKQSIYRW RNGDWKILSE QLDEDFKGFG VNGMTLNYNW RSSKNVINFN NALFALGAQA
LQNDYNASIP PEISEGLKEE QEKIIGAYQD VYQHFPGNKE KSPGYVKANF IEKETDSDWI
EKVLEDLPLR IEQFQEMGYQ ARDISILVRN GKEGGLIADA LMAYRASENV KEGINYDVIS
NDSLYLKNSS VISFLAHLLS YFVYPDDKIN LGFLKQEYQV YIKNQQTEDK DQLYAISKDE
NTFESDFPDE FTSNIPELKR QALYDLVEKL IYIFKLNERP QDFPFLEAFQ DLVLGFTKTD
APDLNSFVNY WEERKNKEVI SVSDQQDAIR IMTIHKSKGL EFKVVILPFC NWDLDNTRHT
NILWCQPKVE GFNVLDVLPV RYSSSLKETI YYQEYFTEKL HSYIDNLNLL YVALTRAEEA
FISYSPLPAK RDLKNISDLL LHAFENSDNY SSDFNGNKIV SLTQNWNKEG HYFELGELKA
TASKVLPKPK EKRSDYPASL LDDRLKLRSH SADYFDFSEA VSVETFSPVS RGNILHQLFQ
LIEYKEDIAK AVSQLQFEGK LDQIQAEEVS LFAKELLSEP TVAEWFSKGW TVVNERDILL
GKGEVLRPDR VIHKGKEAIV IDFKFGKKKE KSHKTQVLAY KKLIEQLGFE KVRAFVLYGK
LAEIEEV
//
