ID A0A1Y1HQQ5_KLENI Unreviewed; 472 AA.
AC A0A1Y1HQQ5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Cation-chloride co-transporter protein {ECO:0000313|EMBL:GAQ80413.1};
GN ORFNames=KFL_000530390 {ECO:0000313|EMBL:GAQ80413.1};
OS Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ80413.1, ECO:0000313|Proteomes:UP000054558};
RN [1] {ECO:0000313|EMBL:GAQ80413.1, ECO:0000313|Proteomes:UP000054558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ80413.1,
RC ECO:0000313|Proteomes:UP000054558};
RX PubMed=24865297; DOI=10.1038/ncomms4978;
RA Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA Tabata S., Ida S., Kurokawa K., Ohta H.;
RT "Klebsormidium flaccidum genome reveals primary factors for plant
RT terrestrial adaptation.";
RL Nat. Commun. 5:3978-3978(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DF237002; GAQ80413.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1HQQ5; -.
DR STRING; 105231.A0A1Y1HQQ5; -.
DR OrthoDB; 5490251at2759; -.
DR Proteomes; UP000054558; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF100; CATION-CHLORIDE COTRANSPORTER 1; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054558};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..108
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 130..252
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 264..472
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
SQ SEQUENCE 472 AA; 53816 MW; 5720525C162FC357 CRC64;
MFFLLCYAGV NLSCFLLDLL DAPSWRPRWK WHHFLLSGFG ALLCFVIMLI ISWVFTIISV
ILAALIYYYV SVRGKAGDWG DGFKSAYFQL ALRSIRTMGA KQVHPKNWYP IPLIYCKPWG
ILPADVPCHP MLPDFANCMK KKGRGLSIFV SIMEGDYGDC IEEAREATRT LTAYIEYKKC
EAVGDVIVAR TMEDGFRTLI QSMGIGNLKP NMVCMRYPEI WRDERRQLGN IPNQFVNIIR
DCHVGGKAVV IVKGIDDWPG EYQKQYGFID LYWIIRDGGL MLLLAMLLKS KKSFEACKIR
VFCTAQEEGD AEQLKADVKK FLYDLRMEAE VIVLNYRAMD EEQAAAAISE EHAAERQTSA
DAVRQARKRI AARAAAHKAE VQAGDSRRPM DGEYKNYDEE KTSQFLHTTM KLNSIILKYS
RAAAAVVLVS LPPPPPKHPS YNYMEYMDLL VDQVPKLLMV RGYKRDVVTI YS
//
