ID A0A1Y1I1U1_KLENI Unreviewed; 175 AA.
AC A0A1Y1I1U1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 08-NOV-2023, entry version 19.
DE RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1 {ECO:0000256|ARBA:ARBA00013306, ECO:0000256|PIRNR:PIRNR008716};
GN ORFNames=KFL_001690100 {ECO:0000313|EMBL:GAQ83932.1};
OS Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ83932.1, ECO:0000313|Proteomes:UP000054558};
RN [1] {ECO:0000313|EMBL:GAQ83932.1, ECO:0000313|Proteomes:UP000054558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ83932.1,
RC ECO:0000313|Proteomes:UP000054558};
RX PubMed=24865297; DOI=10.1038/ncomms4978;
RA Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA Tabata S., Ida S., Kurokawa K., Ohta H.;
RT "Klebsormidium flaccidum genome reveals primary factors for plant
RT terrestrial adaptation.";
RL Nat. Commun. 5:3978-3978(2014).
CC -!- FUNCTION: E1-like enzyme which specifically catalyzes the second step
CC in ufmylation. Ufmylation is involved in reticulophagy (also called ER-
CC phagy) induced in response to endoplasmic reticulum stress.
CC {ECO:0000256|PIRNR:PIRNR008716}.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1
CC subfamily. {ECO:0000256|ARBA:ARBA00008451,
CC ECO:0000256|PIRNR:PIRNR008716}.
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DR EMBL; DF237118; GAQ83932.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1I1U1; -.
DR STRING; 105231.A0A1Y1I1U1; -.
DR OrthoDB; 67279at2759; -.
DR Proteomes; UP000054558; Unassembled WGS sequence.
DR GO; GO:0061657; F:UFM1 conjugating enzyme activity; IEA:InterPro.
DR GO; GO:0071568; F:UFM1 transferase activity; IBA:GO_Central.
DR GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR014806; Ufc1.
DR PANTHER; PTHR12921; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR PANTHER; PTHR12921:SF0; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR Pfam; PF08694; UFC1; 1.
DR PIRSF; PIRSF008716; DUF1782; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054558};
KW Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR008716}.
FT ACT_SITE 119
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR008716-1"
SQ SEQUENCE 175 AA; 19821 MW; EDAD7D916DCBC6F7 CRC64;
MEGWDTSTKA VVQKIPLLTV KAGPRDGEDW KKRLKEEYQA LIAYMQMNKA NDNDWFRISA
ANPEGTKWKG KCWYIHNLLK YEFDLQFDIP ATYPATAPEL ELPELDGKTA KMYRGGKICL
TIHFKPLWAK NVPHFGVAHA LCLGMGPWLA AEIPHLVETG MIQHKDNTAK ATPPT
//
