ID A0A1Y1I3K7_KLENI Unreviewed; 653 AA.
AC A0A1Y1I3K7;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=GTPase {ECO:0000313|EMBL:GAQ83761.1};
GN ORFNames=KFL_001610030 {ECO:0000313|EMBL:GAQ83761.1};
OS Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ83761.1, ECO:0000313|Proteomes:UP000054558};
RN [1] {ECO:0000313|EMBL:GAQ83761.1, ECO:0000313|Proteomes:UP000054558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ83761.1,
RC ECO:0000313|Proteomes:UP000054558};
RX PubMed=24865297; DOI=10.1038/ncomms4978;
RA Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA Tabata S., Ida S., Kurokawa K., Ohta H.;
RT "Klebsormidium flaccidum genome reveals primary factors for plant
RT terrestrial adaptation.";
RL Nat. Commun. 5:3978-3978(2014).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. TrmE GTPase family. {ECO:0000256|ARBA:ARBA00011043,
CC ECO:0000256|RuleBase:RU003313}.
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DR EMBL; DF237110; GAQ83761.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1I3K7; -.
DR STRING; 105231.A0A1Y1I3K7; -.
DR OrthoDB; 5478664at2759; -.
DR Proteomes; UP000054558; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0030488; P:tRNA methylation; IBA:GO_Central.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IBA:GO_Central.
DR CDD; cd04164; trmE; 1.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 2.
DR HAMAP; MF_00379; GTPase_MnmE; 1.
DR InterPro; IPR031168; G_TrmE.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR004520; GTPase_MnmE.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR025867; MnmE_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00450; mnmE_trmE_thdF; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF12631; MnmE_helical; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF116878; TrmE connector domain; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003313};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003313};
KW Reference proteome {ECO:0000313|Proteomes:UP000054558};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694,
KW ECO:0000256|RuleBase:RU003313}.
FT DOMAIN 77..208
FT /note="GTP-binding protein TrmE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10396"
FT DOMAIN 211..650
FT /note="MnmE helical"
FT /evidence="ECO:0000259|Pfam:PF12631"
FT DOMAIN 305..405
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT REGION 412..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 70322 MW; CDBB2F9A0006B09A CRC64;
MCPSDQHYPA FSSRTGAFSP KIASLPFLRW KQVQLRCSAV NQGPNYPPQW TERGYRTWRQ
PETEAAETSG QHGDFDTIAA IVTPLALGDQ PGAVAIVRLS GPKTVDMVRK IFKPFRRKDT
QGGESMEWHP ESHKVEYGKI VDASGALVDE VIMVPMLAPR SYTREDVIEI QCHGGQVPVR
RVLNTCLEAG ARLAKPGEFT LRAFLNGRLD LSQAEGIADL INARTTQAAE SALSTMQRGL
SSFVTSLRAE CIDLLVEMEA RLDFDEELPP FDVPALIERI HTISQRLQKA LATAQRGRLL
QAGMRVAIIG RPNVGKSSLL NAWSNSDRAI VTNIPGTTRD VVEAAVSVGG IPVYLLDTAG
IRDTADAVEK IGVERSKDAA AGADVVVMVV SAADGWTERD DVILSHVWGA SSSGSARKSL
SGPMSVGGVG PRTEGKGPVT EEWSHASDER PAVRSLSDGA SEPYTQTATE KSASQVRQTS
PADQNTERDP SSSTDSAREP AGSASNGAPH ERLQTARISG PPAILVVNKV DRAPESQVAV
PDSWRQVFAR RIATCARDGV GLVELERALL EIVGAGEATA EGISWAVNQR QAEQLVRASE
ALQRLVASIE DDLPIDFWTV DVREAALALG QISGDDVTEE VLDGIFSRFC IGK
//
