ID   A0A1Y1I720_KLENI        Unreviewed;       805 AA.
AC   A0A1Y1I720;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=E3 UFM1-protein ligase 1 homolog {ECO:0000313|EMBL:GAQ86755.1};
GN   ORFNames=KFL_003090120 {ECO:0000313|EMBL:GAQ86755.1};
OS   Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC   Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC   Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX   NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ86755.1, ECO:0000313|Proteomes:UP000054558};
RN   [1] {ECO:0000313|EMBL:GAQ86755.1, ECO:0000313|Proteomes:UP000054558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ86755.1,
RC   ECO:0000313|Proteomes:UP000054558};
RX   PubMed=24865297; DOI=10.1038/ncomms4978;
RA   Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA   Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA   Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA   Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA   Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA   Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA   Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA   Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA   Tabata S., Ida S., Kurokawa K., Ohta H.;
RT   "Klebsormidium flaccidum genome reveals primary factors for plant
RT   terrestrial adaptation.";
RL   Nat. Commun. 5:3978-3978(2014).
CC   -!- SIMILARITY: Belongs to the UFL1 family.
CC       {ECO:0000256|ARBA:ARBA00010789}.
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DR   EMBL; DF237258; GAQ86755.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1I720; -.
DR   STRING; 105231.A0A1Y1I720; -.
DR   OrthoDB; 199903at2759; -.
DR   Proteomes; UP000054558; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0061666; F:UFM1 ligase activity; IEA:InterPro.
DR   GO; GO:0071568; F:UFM1 transferase activity; IBA:GO_Central.
DR   GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:GO_Central.
DR   InterPro; IPR004143; BPL_LPL_catalytic.
DR   InterPro; IPR018611; Ufl1.
DR   PANTHER; PTHR31057; E3 UFM1-PROTEIN LIGASE 1; 1.
DR   PANTHER; PTHR31057:SF0; E3 UFM1-PROTEIN LIGASE 1; 1.
DR   Pfam; PF09743; E3_UFM1_ligase; 1.
DR   PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Ligase {ECO:0000313|EMBL:GAQ86755.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054558};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..137
FT                   /note="BPL/LPL catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51733"
FT   REGION          398..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          549..583
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        405..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..461
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   805 AA;  86413 MW;  DE3430AAAAB70712 CRC64;
     MDEELRKLQE LFSQAQEVKS TVRLSERNVI ELVNKLKQLG LLGDDLLHTV NGKEYITVNQ
     LRKEMASEVH RQGRISLVDL ATNLGVDLFH IERQADALVA EEADTSLVQG ELLTTGYWDN
     LAEEIDESLQ ETGQVSIGEL ARQFNVGVEL LTGAITARLD TKIHGKLDSG MLYTPAHVAR
     IKAMVRGAMR GVTVPCSVPD VWASLHRLQQ REDKESVAGV GGDSLYSTVL AELIAEGELK
     GTLSGGKTLW TPAVFSRSQR ESVENFYSQN GHIAYDSLRK LAIPNPKQYL QDKYAEGIPL
     ETVFVHPSLV GQLDAAVEEA VANGTWCEAE QLVPSSLSAA DTAKLLAQCP SVEKATKTKS
     AVLVLDTCLV AESLLKDCIE KFDTLARTKA AAVLLAKKPS KAANAATAER NSQASTSAAG
     NDDSEDEGGR TKRGGKKGRR GAPSKSAEVD EEEEETRGGK GAKKGRRNKA GKGGAASTEP
     AAEENETRGA PTDTEMEDCL LEWYPDLEGA GAGTSDDSNK LARALVRRLR PTVLATFVAA
     KKAAFTAGAE ERRKRRDALL QKLEEANLRL QLFAKALELF EEDAATGPLL QRHLLRTTAT
     EATDALLMSE REAEAEDGEE REPTAGPLSA AERASAVRAL PKGVAERARA MLAALDGKDV
     AAFQEALDHT AEACGVRLKK LDKKLERSLL HAHRKTLVAQ LEAENSAVAS LPLVVAALYA
     QVLSRALQAP GRAMAAAIAR LKDELPPASF ATLNEYHRAT VDLLAATAAS ASEGDDTKLM
     GQKEESLNSQ LASLKALVLG SSEGS
//