ID   A0A1Y1ICE8_KLENI        Unreviewed;      1109 AA.
AC   A0A1Y1ICE8;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Karyopherin beta 3 {ECO:0000313|EMBL:GAQ88590.1};
GN   ORFNames=KFL_004420050 {ECO:0000313|EMBL:GAQ88590.1};
OS   Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC   Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC   Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX   NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ88590.1, ECO:0000313|Proteomes:UP000054558};
RN   [1] {ECO:0000313|EMBL:GAQ88590.1, ECO:0000313|Proteomes:UP000054558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ88590.1,
RC   ECO:0000313|Proteomes:UP000054558};
RX   PubMed=24865297; DOI=10.1038/ncomms4978;
RA   Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA   Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA   Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA   Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA   Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA   Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA   Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA   Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA   Tabata S., Ida S., Kurokawa K., Ohta H.;
RT   "Klebsormidium flaccidum genome reveals primary factors for plant
RT   terrestrial adaptation.";
RL   Nat. Commun. 5:3978-3978(2014).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; DF237391; GAQ88590.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1ICE8; -.
DR   STRING; 105231.A0A1Y1ICE8; -.
DR   OrthoDB; 24319at2759; -.
DR   Proteomes; UP000054558; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   InterPro; IPR041653; Importin_rep_4.
DR   InterPro; IPR041389; Importin_rep_6.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR   Pfam; PF13646; HEAT_2; 1.
DR   Pfam; PF18808; Importin_rep_4; 1.
DR   Pfam; PF18829; Importin_rep_6; 1.
DR   SMART; SM01349; TOG; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054558};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          37..108
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REPEAT          413..451
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ   SEQUENCE   1109 AA;  122117 MW;  9DA1FFA5EBDA0BA0 CRC64;
     MAAVSPAVSA VLGPDLSNAE TLLKMLMSPS NAERGQAESL FEECKKHPDP LVTTLVLVLH
     RSTVQENRAM AAVLLRKVIT KDQVSLWPQL STATQDGVKS GLLQCVQKEE SKTICKKLCD
     SIAELAAGIF EEGLWPELLP FMFNSVQSQD DRLRWIALLI FSQLAAYLGS KLQPYLQTLH
     AVFQEGMSSS SSSDVRTAAL RATTAFVSTL ETASERDKFQ DLLPAMMQTL TVALNSGEEA
     TAQEALEMFI EIAGTEPRFL RKQLVDVVAA MLQIAEAQQL EDSTRHLAVE FLVTLAEARD
     KAPGMMRKLP HLIGRLFAVL LNFLLSIEDE PKWHTADSEE EMITDEDNYD VGMECLDRLA
     ISLGGNTILP VASQLVPACL IDQDWKKRHA GLIALAQIAE GCAKVLLKDM GPVVEMILAS
     LGDPHPRVRW AAINALGQLS TDLGPNLQKK FHARVLPALL NSMDDFQSPR VQAHASAAVL
     NFTENCAPEI LEPYLDSLIN KLLVLLQQGG RRMVQEGALT ALASVADCAQ NLFDKYYSAV
     MPYLKSILLH ATDKTHRMLR AKSMECISLV GMAVGKDKFR ADAKEVMDVL IKLQVADMDD
     DDPTISYMLQ AWARLCKCLG QEFLPYMEIV MPPLLRSAQL KPDITVRNAD SDNEDEDEED
     ESIETIPLGD KRIHIRTSVL EEKATACNML CCYADELKEG FAPWVEQVTE IMVPLIKFYF
     HEEVRKAAVS AMPELLRSAE LALKKNGQDI QQLKKLADVI IGSLVESLGK EPEAEIVASM
     LESLGECIQV AGPLLDPGQV KSIVDNFQEV ITETLKRKEE KHARSRTEDF DEEEGEMLEE
     EIEQEDEVLE QLAECLGKML KVYKAQLLPL IATLVPFLAP LLEPKRPAAE RRAIICIFDD
     LIEQTGEPGN QYFDLFMPAM LHSATDPHAD TRQAAVFGLG VCAQFCGARF RGVAHEALAK
     LNAVISAEGA REEESVLATE NAISAVGKIC EFQRDCIDAK LVLPAFLSCL PIKNDQLEAK
     LVHEYLVSLV EKSDPDLLGP GQQNLPKVIA VFAEVLTEKD LVTDAAAGRI RAVLRHLQNS
     LPVDVVRATF GALSPAQQAA LQSAMSVQG
//