ID A0A1Y1IIK7_KLENI Unreviewed; 650 AA.
AC A0A1Y1IIK7;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE RecName: Full=Proliferating cell nuclear antigen {ECO:0000256|RuleBase:RU000641};
GN ORFNames=KFL_006770030 {ECO:0000313|EMBL:GAQ90710.1};
OS Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ90710.1, ECO:0000313|Proteomes:UP000054558};
RN [1] {ECO:0000313|EMBL:GAQ90710.1, ECO:0000313|Proteomes:UP000054558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ90710.1,
RC ECO:0000313|Proteomes:UP000054558};
RX PubMed=24865297; DOI=10.1038/ncomms4978;
RA Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA Tabata S., Ida S., Kurokawa K., Ohta H.;
RT "Klebsormidium flaccidum genome reveals primary factors for plant
RT terrestrial adaptation.";
RL Nat. Commun. 5:3978-3978(2014).
CC -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC and is involved in the control of eukaryotic DNA replication by
CC increasing the polymerase's processibility during elongation of the
CC leading strand. {ECO:0000256|RuleBase:RU000641}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000641}.
CC -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000256|ARBA:ARBA00010462,
CC ECO:0000256|RuleBase:RU003671}.
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DR EMBL; DF237626; GAQ90710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1IIK7; -.
DR STRING; 105231.A0A1Y1IIK7; -.
DR OrthoDB; 118939at2759; -.
DR Proteomes; UP000054558; Unassembled WGS sequence.
DR GO; GO:0043626; C:PCNA complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030337; F:DNA polymerase processivity factor activity; IBA:GO_Central.
DR GO; GO:0006272; P:leading strand elongation; IBA:GO_Central.
DR GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR GO; GO:0019985; P:translesion synthesis; IBA:GO_Central.
DR CDD; cd00577; PCNA; 1.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR000730; Pr_cel_nuc_antig.
DR InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR NCBIfam; TIGR00590; pcna; 1.
DR PANTHER; PTHR11352; PROLIFERATING CELL NUCLEAR ANTIGEN; 1.
DR PANTHER; PTHR11352:SF0; PROLIFERATING CELL NUCLEAR ANTIGEN; 1.
DR Pfam; PF02747; PCNA_C; 1.
DR Pfam; PF00705; PCNA_N; 1.
DR PRINTS; PR00339; PCNACYCLIN.
DR SUPFAM; SSF55979; DNA clamp; 2.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|RuleBase:RU003671};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003671};
KW Nucleus {ECO:0000256|RuleBase:RU000641};
KW Reference proteome {ECO:0000313|Proteomes:UP000054558}.
FT DOMAIN 12..133
FT /note="Proliferating cell nuclear antigen PCNA N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00705"
FT DOMAIN 136..241
FT /note="Proliferating cell nuclear antigen PCNA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02747"
SQ SEQUENCE 650 AA; 70957 MW; A511FB9804A2291F CRC64;
MEPDRARYPL HIKTVQGSSL KGLFEVLKEL LNDVNVVVNQ SGIKILAMDS AQVTLCHCLL
EAQNFEVFHC PETVVIGLNV QNLYKLLKTV SSQDTLTLQI ESDSPNDLEI IIQNSEKKSK
TFFKLRLLDI DDDRLKVPNV EMTTCITMAS VDFQRLIRDM LTVGSVLRVR VKKREVIFET
SGDFASQRTI LETSEDTKVN ESDDEIDLSF SLKLLSLFSK ASTLSTTCSL WLQADFPLIV
QEMGTIDDVQ FLLENSVEET YLFIVDSGTR DRTIYPEPNL YAVTFDSPFQ NVIGIDIIDG
TIPRTQYAVD TACNKLCIDY GTGPVTVELT TGDHTDTSLV SDVNARLAAL PGCTVTARSV
STPPELKNLI TFTAPNIPFH IIADERSTVK PVLGFDEYAA RHKYLGDRFA CKDPLNAPAI
YTSVAKDPMP ATTFSTQESA EDVISFADPS SPTTRRLIAI RFSPTQSGLI DSITLACNVV
APSSGTVTFY LASDDEVESA PGAPICPPVS MPAREFGDYG RTTLRFSSEM GLTVGRNAWL
VVSGGRASDG LYAGSSGNAL AKASSDGGGS WSTIPGGLIP LMSVQVIQST QTITGPGILN
LVGDSYCMLR CDEIESHTIR SRAFEKYTFG LARFTLAVVG FAQSHVQRVL
//
