ID A0A1Y1IL33_KLENI Unreviewed; 1235 AA.
AC A0A1Y1IL33;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE AltName: Full=Minichromosome maintenance 9 {ECO:0000256|ARBA:ARBA00042301};
GN ORFNames=KFL_005670050 {ECO:0000313|EMBL:GAQ89831.1};
OS Klebsormidium nitens (Green alga) (Ulothrix nitens).
OC Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae;
OC Klebsormidiales; Klebsormidiaceae; Klebsormidium.
OX NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ89831.1, ECO:0000313|Proteomes:UP000054558};
RN [1] {ECO:0000313|EMBL:GAQ89831.1, ECO:0000313|Proteomes:UP000054558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ89831.1,
RC ECO:0000313|Proteomes:UP000054558};
RX PubMed=24865297; DOI=10.1038/ncomms4978;
RA Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M.,
RA Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M.,
RA Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T.,
RA Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S.,
RA Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M.,
RA Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M.,
RA Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H.,
RA Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y.,
RA Tabata S., Ida S., Kurokawa K., Ohta H.;
RT "Klebsormidium flaccidum genome reveals primary factors for plant
RT terrestrial adaptation.";
RL Nat. Commun. 5:3978-3978(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|RuleBase:RU004070}.
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DR EMBL; DF237516; GAQ89831.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1IL33; -.
DR STRING; 105231.A0A1Y1IL33; -.
DR OrthoDB; 147095at2759; -.
DR Proteomes; UP000054558; Unassembled WGS sequence.
DR GO; GO:0042555; C:MCM complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630:SF48; DNA HELICASE MCM9; 1.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000054558}.
FT DOMAIN 312..511
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
FT REGION 658..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..698
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..795
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..871
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1062
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1102..1142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1235 AA; 132707 MW; 82B0E46FD2B73C53 CRC64;
MARASQEAVV HDEEYVDALY KFAMEYHAQD LAEILLKPDD DLHYAVHVSF QELHGDERFE
AMANLLCCKP RWLLPLFDEA LSKAQVDIAD VHELQEDMSF KAHVHARVTL MECPEMKPSI
SRIRCEDIGR ILAVRGTIIR TGAVKMLEGE REYECAKCKL RFKVTPQLEQ DNKLTLPASC
PSDRTKPCKS VTFNYVDESK VCHDYQEIKI QEEMHGLGVG SVPRSIVAVL QDDLVDYCKA
GDDVEVTGVL CCKWKPVMKG VRCDLEMVIL ANSVRKASAD KAAVDLSPET VYKFQEYWRQ
FLDCPLKGRN GILKGICPQV YGLFTVKLAV ALTLIGGVAR VDKSGTRVRG EPHLLIVGDP
GTGKSQFMKY AAKLSARSVV TTGMGSTGAG LTVTAVRDNG EWMLEAGALV LADGGLCCID
EFDGIREADR ATIHEAMEQQ TLSVAKAGLV TTLNTRCTVF AVCNPKGQYD PDNTLEVNTS
LAAPLLSRFD IVLVLLDTKN PDWDRIVSSH ILTEHKNAHR ADEDTSISSP TPSALWTIDM
LRSYIYYVKA AFQPTLTPEA ERVIVNYYQL QRRSNAGNRN QARTTIRMLE SLVRIAQAHA
RLMFRHEVLR TDAVVAVVTI ESSMTTSAIL ENMTNALHSS FKDEPDAEYR DIEAQILTAL
GIPPPSDEER AAEMTRGRHE EGPCGDQEGE KDAEVTRGGQ ESEPGTESAA KGAEGNERRE
MGLLVDVGRS FESEDASGED GDLLLRPDSG GLQGRESEPP EALGSQLEMG ERSPSRENED
GGNCENPDRR CGTSEEAQTV RNMGVEDQTV GNDPGVGEAA TWQAEARALE ARLRGFRQAG
VDVSTTDDVG ERQKAERWTR ADGERSGGPS SKRADGCRTG GVSGVRREAD ALLGSDSEAK
GVETGGLHGA PNAPSEGTGV SKNPVTKNAD AENRVAGNPG TELPVCLSPL ARRTSASLAG
AGSGHVGAAG GGHVAAEDGA GPSGDVAVKG KKCAGRGSLS GGSSGEDVSQ AFGGFERRIS
ERGAENAALE REPVSEATGE HAGKCDRPEG ASDRRTDGTG RGHDDFAGQG LETVRADRGV
NVTGQHDANG LTIEPGREPP SSEEAQESSG PARPLSATSR FGSSETSALI RTLTQRLARP
SQKASDPANG VRPPCPEPQL RAPSNQGGLE SNPVAPLADR AVNAASGPKA QAGGLGMLRK
RLQGRRSAEE SEDANWLSDE QWGISSPGAK RARNT
//
