ID   A0A1Y1JMA6_PLAGO        Unreviewed;      1930 AA.
AC   A0A1Y1JMA6;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=DNA repair protein RAD50 {ECO:0000313|EMBL:GAW81962.1};
GN   ORFNames=PGO_114160 {ECO:0000313|EMBL:GAW81962.1};
OS   Plasmodium gonderi.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=77519 {ECO:0000313|EMBL:GAW81962.1, ECO:0000313|Proteomes:UP000195521};
RN   [1] {ECO:0000313|Proteomes:UP000195521}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 30045 {ECO:0000313|Proteomes:UP000195521};
RA   Arisue N., Honma H., Kawai S., Tougan T., Tanabe K., Horii T.;
RT   "Plasmodium gonderi genome.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC       {ECO:0000256|ARBA:ARBA00009439}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAW81962.1}.
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DR   EMBL; BDQF01000012; GAW81962.1; -; Genomic_DNA.
DR   EnsemblProtists; GAW81962; GAW81962; PGO_114160.
DR   OMA; NVILCHH; -.
DR   OrthoDB; 5477220at2759; -.
DR   Proteomes; UP000195521; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR   PANTHER; PTHR18867; RAD50; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195521};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          6..241
FT                   /note="Rad50/SbcC-type AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13476"
FT   COILED          219..319
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          525..569
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1042..1076
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1426..1505
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1551..1585
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1668..1695
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1930 AA;  228505 MW;  84B8E968652A5661 CRC64;
     MTTLEKIGIQ GIRSYGDEEA QELEFASPIT VIYGNNGSGK STIIECLKVS CTGDFPPNAE
     KGKSFIHDPL VSNKMNIRGK INLLLKNYNN KRVGISRSFN LFYCKDKNKK IKHTFRALDN
     NIIIKKGKGQ EDVIITNKCV DINNHIPKLM GVSKALLENV ILCHHEESLW PFSESVKIKK
     KFDELFGDDN FSKILDELIK CKKTMNDMLK RKEYELGTLK DFYEKKNNIT LEIQKNEKEI
     ENSETLMQLH KEEIDQSLNM LQKLKKNNSI LSKLISHMDM YFVLYEKFQF DMENYKNMKE
     IYEEDSKELQ QYAELLQKDL IRCETLIENV HLDIVELEKQ SNLDVYSCDE FDIKERDVIQ
     ESLSQLERRK TNLKNLTKLI FDIDSSTFSM LKRRNIKRKM LSEEYIQLCH FMKSNEPIFV
     YELEKWRFVF SKKPPNFKFN VGYERSSHSS RIAKDEKNQG ENSRGDITSL LHSRTLDEGE
     ITNETSISDN LTNMFLIMEV RKMVRKHVHK LALIRTEVYE NIRERKKILK KKKNLIRKLE
     KWKRRNSKVD KKIAKMKRYQ EKLTQLKWKD KLYESNINNL EKMNQIGCIY DSIELSELNF
     NLIEMGCDIH TYTDNGIERK KEQLKKIQNL KKKLEKMFHI ATSFNTTYKH FLIIQSMNMN
     IISFFHEQWA LFSELAKFSE IYNSIRVDNS DLYAYIENLV LYSDVTNSGL VEEKHEGYKW
     CSDALAGVLW TKGERAIEKV TSEGARGEGK MGEGEIDERE INENEIDENE IDENEIDENE
     IDENEIDENE IDEREIDENE IDEREINENE IDEANGGDMP KGNEIRVSIV HNQVGEITKR
     DKIAKLKKCT SLENPCEVNS SKCEYKEYPK RIVNIKNKKR MNEFRDESCC SRLKRKKKII
     EFFPQYGKNK NYMKILNDLL NVYVNKYEKK TNNIESKTLK LKEKLILICR ELDIVNNQTE
     KYPEVLSQFR RMLEKINFKN MNDFINHFCH FKINIKKIKM DLITLRSKEE SLKFFLQDAQ
     NLNSCHFCKS SISTSELSSF SILNAEKQRE EINQELEEKQ KLLTNLKSEK KEMKNLLVYY
     YHNVEPICRD NNVLSDYLHF MKNELVNVQN GIHNCSMKIN NINENYELLM RLKKRCNHLV
     ERETNVISMQ QQLYARHRKV KLALRNYRDI FSQGKECVQF FRSFLDELEV GTAEVEAAEV
     VAAQVEDVGL IMEVKQFLLK SLPQYINLYD NKEIMNFFFQ KVSEHVESHL VRQFIEHESN
     DIVEEESENH VMKKNKKYVD AFENSNLDEV GKTLTSQTEC DSTIENSRDT SSHDEGEEDL
     IMRYSKSHLE GSLLENKDLL SNCTNGGEKS IILIKNLHAE WVKEKTIKRS EKCESIIMNN
     INVMHMLKSV NLKNKEFLSL YDKLLLCINL EEMKKKQEID MIHRMKSVIK DRKEYVKKKI
     DELQNNLERE KQIRESINKS EKYIAYYLGK KICIQKKEET ILTLMKRVQL EEKNMRRNIR
     RKRNDILFLN KLYYIKINII KQLNNLLTEI NTEKEVKGNQ LRRVIEKIQN NQVIKNESNE
     LVNKINKKKE QILCLQEEKI NIEKMHHNVV MNTNLKKMHE NFLNHQKNFI SSLNEFKNTF
     FLHDKQEKQL NEINSMIKQL DEMYETDCDI YKFINESFTF LNYKNELLEL AYREEDNLRE
     KIERHTKSVT DLKMKEAEMK GKIELRKEYV EKLISDRNSD SYTNIEKKYK KKIIEIFVYK
     NVIKDICNFY NSFDQAIIKF HSLKMQEINI SIKNLWRRVY NSADIDYIYI KSDIQTENNG
     KIQQRRSYNY RVVMVKDNCE LDMKGRCSSG QKVLSSIIIR LALAESFSIK CGILALDEPT
     TNLDKSNSKN LASLIANIVD IRKESSSFQL ILITHDTYFV DILSQYGLTN CFYKIRKDNM
     GYSKIIKIRN
//