ID   A0A1Y1JNB9_PLAGO        Unreviewed;       972 AA.
AC   A0A1Y1JNB9;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=DNA replication licensing factor MCM2 {ECO:0000256|ARBA:ARBA00018925};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=PGO_133100 {ECO:0000313|EMBL:GAW83038.1};
OS   Plasmodium gonderi.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=77519 {ECO:0000313|EMBL:GAW83038.1, ECO:0000313|Proteomes:UP000195521};
RN   [1] {ECO:0000313|Proteomes:UP000195521}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 30045 {ECO:0000313|Proteomes:UP000195521};
RA   Arisue N., Honma H., Kawai S., Tougan T., Tanabe K., Horii T.;
RT   "Plasmodium gonderi genome.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAW83038.1}.
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DR   EMBL; BDQF01000014; GAW83038.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1JNB9; -.
DR   EnsemblProtists; GAW83038; GAW83038; PGO_133100.
DR   OMA; LKDWPYS; -.
DR   OrthoDB; 5476523at2759; -.
DR   Proteomes; UP000195521; Unassembled WGS sequence.
DR   GO; GO:0042555; C:MCM complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   Gene3D; 2.20.28.10; -; 1.
DR   Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR031327; MCM.
DR   InterPro; IPR008045; MCM2.
DR   InterPro; IPR001208; MCM_dom.
DR   InterPro; IPR041562; MCM_lid.
DR   InterPro; IPR027925; MCM_N.
DR   InterPro; IPR033762; MCM_OB.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR   PANTHER; PTHR11630:SF44; DNA REPLICATION LICENSING FACTOR MCM2; 1.
DR   Pfam; PF00493; MCM; 2.
DR   Pfam; PF17855; MCM_lid; 1.
DR   Pfam; PF14551; MCM_N; 1.
DR   Pfam; PF17207; MCM_OB; 1.
DR   PRINTS; PR01657; MCMFAMILY.
DR   PRINTS; PR01658; MCMPROTEIN2.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00350; MCM; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50051; MCM_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195521}.
FT   DOMAIN          487..717
FT                   /note="MCM"
FT                   /evidence="ECO:0000259|PROSITE:PS50051"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..28
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   972 AA;  111550 MW;  E9B8E6EC2EFBD2D4 CRC64;
     MEEKKKVEED LESNKYDIDE EDLLEDEGRL NEDERQAELE GESLFEEDEG FIFGVDDEKK
     EMQKLRNLGL DNDEYDDDFI DDELDYEDNL KARRAAERHI QMQRKQEGKY EKNKFWKTLE
     DQLEGDDEEE DIFDKVAEKV AKRRENMHLS AEETDIPDLS NLESAKICLS VNPKDVIFDE
     RYQQAADTCF RYFLHKFSLK DSMGIHLDQS IQSETNEDDN MNNSYQYYID KIEKMILNDK
     HTLIVSAKHM IQFHCENLVQ WIEFKPEQIL EVLHECLMVE AYRISPKLYK GRLCKVVLKD
     WPYSTQLRNL RCTELNTLIK VRGVCIKRGY VLPKLRVMYL KCNSCDTTLS EVPIYFTDGK
     KPVLPRRCPH CQSATFSVDR VKTAYTDFQK ITLQESPSSV PAGRAPRQRE VIVTGDLVDK
     VKPGEEVEVL GIYKTKYDIG LNIKYGFPIL QTEIEANNIE RKEDIQLSEL TEDDIKDILK
     LSKDPNIRER IITSIAPAIW GHKDIKTSIA YALFGGVQKG GDKNNVKNSD TNNFGIQNKD
     ILNNFKGGHT IRGDINVLLL GDPGLGKSQV LQYVHKTNLR TVYTTGKGAS AVGLTAGVRK
     DHTTNEWTLE GGALVLADEG ICIIDEFDKM TDKDRVSIHE AMEQQSISIS KAGIVTTLRA
     RCAVIAAANP IYGRYDPTLT FKENVDLSDP ILSRFDLITV LRDIPNVDED FYLAEYVVTN
     HQLSHPKLEN TQNYQKRIEN LKNVIVSSSA YEPIPQDLLQ KYIIYARTNC KPGLSDVPYA
     EISAKLSNFY SRVRQKASAS GGYPLTLRHI ESIIRIAEAN AKMRLSQQIV SKDVDYAIAT
     LLESYVSCQR FAVAKQLSKE FARYRALFRG GHEVLCELVR RTIQQTIQRE NLKNASAKDF
     QNDAESGTEN ETEFLNPNNV FLPLQIFMKT AMQNKFSEYQ IVNWMKSKVF NEHYALIKRD
     GVEGIISKKF KM
//