ID   A0A1Y1RGA1_9BACT        Unreviewed;      1255 AA.
AC   A0A1Y1RGA1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=B6244_11025 {ECO:0000313|EMBL:OQY27306.1};
OS   Candidatus Cloacimonetes bacterium 4572_55.
OC   Bacteria; Candidatus Cloacimonadota.
OX   NCBI_TaxID=1971726 {ECO:0000313|EMBL:OQY27306.1, ECO:0000313|Proteomes:UP000192623};
RN   [1] {ECO:0000313|Proteomes:UP000192623}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Dombrowski N., Seitz K., Teske A., Baker B.;
RT   "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT   hydrothermal sediment communities.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQY27306.1}.
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DR   EMBL; NBMB01000043; OQY27306.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1RGA1; -.
DR   STRING; 1971726.B6244_11025; -.
DR   Proteomes; UP000192623; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 2.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00211; Guanylate_cyc; 2.
DR   Pfam; PF13424; TPR_12; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50005; TPR; 2.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          25..160
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REPEAT          905..938
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          1196..1229
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   1255 AA;  143140 MW;  CFA1E2F9A6B25AA0 CRC64;
     MKNLAPHFIL ENYQNGIHQG ELATAGLFID ISGFTQLTET LMQHGTVGSE RLAEILGDVF
     APLVRSVYDK GGFITKFAGD AFTALFPRLD GCNRALAAGW DIHQEFENNP IKKTSFGEFT
     FAVKVGVSVG KSQWGIFDIP DAQRAYYFKG SAIDGCALAE HHAEKGDVVI SREFYDQVKD
     QVIAEPIDDA DDSIQFVRVT SVTGDLSRYQ VAVDDSPFDP PVFPDELVAR FTAPEILDLK
     SPGEFRNLST VFISLRAVPD HDQLEDFVNI LMDLKRQYGG YLTGIDFGDK GCNFMMLWGA
     PISFENNVPR ALNFALDLRK QSNEKLRIGI TQRLMFSGFA GTDLRGEYTG YGRGVNLAAR
     FMMAANWDEI WIDEETHALA ESLFEAHYFD KMRFKGFADP LSIYRLSRRR EFTEIVRFSG
     EMVGRQIELD CMKVFIDPLF HSQFAGLIYV YGEAGMGKSR LIYEVKKNIE EKSQKTPRIK
     WFHCPCEEII RQSLNPFKYA LRRYFNQSSG RSFETNKADF EKILTTLSDS LKLVDSEQAD
     ELLVNLIRIR SFLGAMIDLH WEDSLYEQLD PESRFENSMM AFKSLIKAES LIQPVVVEIE
     DGHWIDSDSQ RMLSVLIRNL EHEPIVIIAA CRYQDDGSLF QFDLEREIRQ ETIDLNYLAW
     QGVKDFTRQI LGDEPSPELV DLLMERTQGN PFFVEQMAHY FKERDLLEPR CNIQGKPIGL
     KPETAGAPIP TTINATLIAR LDRLTTEVKQ VIQTAAVLGR EFEVKIVSGI LISDLKRGPR
     LEKTDDLSQK VRKIEEENVW SPLNEIRYIF HHALLRDVAY NMQLQARLRE LHRMAGDAFE
     AMHHLDLAPY YGDIAYHYEK SETEDKALIY LIKAGNKAKD EFANDHGLDY YRRAYKLCKK
     YEDQAYILES LGDILQLTAK YQKAIENYER VRQLAHEHSD RARIALADTH LASIQNYIGK
     FDRSIELQLG ALEVYRELND QRGIALALHG IGTSCMYQQK FDQAYSYLEQ ALAIRREIGE
     KNSQARTLMN IGALHYYKGD LNISLDYYHR AKNIFVQTND LKMQTKLASN LGALYKALSD
     TLSGQKKEEA TKNALVNYKE AERIAEKIGD LQNLTIVLNN LGGFSWNTLD NLPMSYDYFY
     KSMQISREIY DRVGLAISLG SLGEVSLSMN RYDQGVLFCQ EAVQITEETD DALRNADILI
     TLGKLFRKKE RFSDAIASFE SASRLADSIE NESLRLKSDH ELEDLYGSAD CSDCA
//