ID   A0A1Y1RMF2_9MICC        Unreviewed;       620 AA.
AC   A0A1Y1RMF2;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Choline transporter {ECO:0000313|EMBL:ORC15200.1};
GN   ORFNames=A7979_08360 {ECO:0000313|EMBL:ORC15200.1};
OS   Rothia nasimurium.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Rothia.
OX   NCBI_TaxID=85336 {ECO:0000313|EMBL:ORC15200.1, ECO:0000313|Proteomes:UP000192359};
RN   [1] {ECO:0000313|EMBL:ORC15200.1, ECO:0000313|Proteomes:UP000192359}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PT-32 {ECO:0000313|EMBL:ORC15200.1,
RC   ECO:0000313|Proteomes:UP000192359};
RA   Gaiser R.A., Van Baarlen P., Wells J.M.;
RT   "Draft genome sequence of a porcine commensal Rothia nasimurium.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC       {ECO:0000256|ARBA:ARBA00005658}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORC15200.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LXWF01000045; ORC15200.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1RMF2; -.
DR   OrthoDB; 9775735at2; -.
DR   Proteomes; UP000192359; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR   InterPro; IPR000060; BCCT_transptr.
DR   NCBIfam; TIGR00842; bcct; 1.
DR   PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR   PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR   Pfam; PF02028; BCCT; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192359};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        188..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        226..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        314..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        405..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        445..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        471..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   620 AA;  66988 MW;  D6128B8823CC8B56 CRC64;
     MREGSLAPRV FIPAAVIMAV FIGITLAFPE KTKSIFDALQ ADVINYFGWY YVAIVAFFVI
     FALYLGFSRM GDVKLGDDND EPAYSFSTWF AFLFAAGMGI GLVFYGATEP LMHYVDPRPG
     VGNGTSEEIA QAAMSQSFLH WGLHPWAIYV IVGLAIAYAT HRLKLPLSIR YALKPLFGDR
     VKGGAGDLID VVALVGTLFG VATSLGLGVM QIAAGLGYMN IPAQGNAWLV GIIIALMAIT
     MFSVVTGLEK GMKWLSNGNL ILAAIVCLFV LVVGPTLFLS RNFIGSIGDY LQNVVAMTFE
     TLALYGVEGE QFQAAWTTFY WGWWISWSPF VGMFIARVSK GRSVREFVIG VLLVPALTSF
     FWFSVLGGTA LHQEIFGSQS LLNEDGSVSA ENALFEMFHN LPGGAILTAG AVLLITVFFV
     TSADSGALVL GMLSTNGSPE PKTWIRVFWV LVAAATAISL VVIGGTDSLT AIQTVAILTA
     LPFSVVIVLM CISLYKALSV EHRLFVRAQR RNARHEIEAS LTEHIDDRVN VLVAEGVEDK
     VTAAVGEHLD ERLDGHLEAA LEEAVDKAVE AKVEEAVEKA VDEVALQVDA NTAAIEQIRA
     VTGSIPVAKP QDIKQTPWNK
//