ID A0A1Y1RN17_9MICC Unreviewed; 368 AA.
AC A0A1Y1RN17;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=A7979_04930 {ECO:0000313|EMBL:ORC15964.1};
OS Rothia nasimurium.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Rothia.
OX NCBI_TaxID=85336 {ECO:0000313|EMBL:ORC15964.1, ECO:0000313|Proteomes:UP000192359};
RN [1] {ECO:0000313|EMBL:ORC15964.1, ECO:0000313|Proteomes:UP000192359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PT-32 {ECO:0000313|EMBL:ORC15964.1,
RC ECO:0000313|Proteomes:UP000192359};
RA Gaiser R.A., Van Baarlen P., Wells J.M.;
RT "Draft genome sequence of a porcine commensal Rothia nasimurium.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORC15964.1}.
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DR EMBL; LXWF01000041; ORC15964.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1RN17; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000192359; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000192359}.
FT DOMAIN 99..357
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT REGION 77..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 39766 MW; 8F8DC217943D41E0 CRC64;
MTPAPEKVTP LFQFASQGKV LTVDTACELH APITPELISD FLTAGAAHRI LCGIIPFDTL
QPSTLWITDQ YRWESSSATE NPVATSTTQR NAAPSRSHDQ QYLSAVAHAL QLIPKAGVHK
IVLARQQHLS HARGIGSDAA AQHTFTRLLS ACPTADVFRA YTGQETHWVG ASPEVIADVQ
DRRFTTHPLA GSLPKAVEPS PTRATSLLTT SEKDLREHAY VVEYISEVLK KIGLTDLNMP
DKPTITETDS MWHLGTPIAA TTSEGLSSLD IALALHPTPA VAGVPLESAL NYISQLEQEP
RSYYSGLVGW MDGEGNGRWS LVLRCARHRP DCTTLFAGAG IVAGSQPTLE LQETEAKMQT
VLHALNAA
//
