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Database: UniProt
Entry: A0A1Y1RWR1_9SPIO
LinkDB: A0A1Y1RWR1_9SPIO
Original site: A0A1Y1RWR1_9SPIO 
ID   A0A1Y1RWR1_9SPIO        Unreviewed;       483 AA.
AC   A0A1Y1RWR1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   16-JAN-2019, entry version 11.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=B4O97_11710 {ECO:0000313|EMBL:ORC34608.1};
OS   Marispirochaeta aestuarii.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae;
OC   Marispirochaeta.
OX   NCBI_TaxID=1963862 {ECO:0000313|EMBL:ORC34608.1, ECO:0000313|Proteomes:UP000192343};
RN   [1] {ECO:0000313|EMBL:ORC34608.1, ECO:0000313|Proteomes:UP000192343}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JC444 {ECO:0000313|EMBL:ORC34608.1,
RC   ECO:0000313|Proteomes:UP000192343};
RA   Shivani Y., Subhash Y., Sasikala C., Ramana C.;
RT   "Draft Genome sequence of Marispirochaeta sp. strain JC444.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ORC34608.1}.
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DR   EMBL; MWQY01000012; ORC34608.1; -; Genomic_DNA.
DR   Proteomes; UP000192343; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000192343};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192343}.
FT   DOMAIN      174    303       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      386    455       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     182    189       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   483 AA;  55050 MW;  EBF0472E2A7DE2EA CRC64;
     MNSVDWDYSL FWKEALQQLR HDLSEQEFMM WFKNLRYESS RQDSIILAVP SVFYRDQVKQ
     RYQRIIESKL QELSGSPIGI DYVIQAMESA VPTDNNGNNG NIKEIRTEEV SRAVQPNAAP
     PIQTRASVAA ERTLPRQKHP HLRGDYTFEN FVIGENNSFA ANAAIAIAKN PGTSYNPCLI
     YGGVGLGKTH LVQSIGNAAH MNFDAFKVVY VTSETFTNEF IQAIKDGKNA QFKSRYRNVD
     LLLIDDIQFL QGKDQTQEEL FHTFNALYDA NKQMVFTCDR PVSELKNLTA RLQSRFERGL
     NVDLQPPNFE TRYAILKRKI EEKGVDISDE VITLICNRIT TNVRDLEAAL TKLIAYADLL
     NKRVTLEIAE QQLKDVFNNT RTGNISIDVI QKVVADHYSL SHNDMRGKKR TKAIAFPRQI
     AMYIVREITE YSTTEVGLAF GGRDHTTVMH ACQRVESRMK TDSALEPTIQ QLIRSIKEYG
     TNS
//
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