ID A0A1Y1SII0_9GAMM Unreviewed; 994 AA.
AC A0A1Y1SII0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=ATO7_06275 {ECO:0000313|EMBL:ORE89464.1};
OS Oceanococcus atlanticus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Oceanococcus.
OX NCBI_TaxID=1317117 {ECO:0000313|EMBL:ORE89464.1, ECO:0000313|Proteomes:UP000192342};
RN [1] {ECO:0000313|EMBL:ORE89464.1, ECO:0000313|Proteomes:UP000192342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=22II-S10r2 {ECO:0000313|EMBL:ORE89464.1,
RC ECO:0000313|Proteomes:UP000192342};
RA Lai Q., Li G., Shao Z.;
RT "Oceanococcus atlanticus 22II-S10r2 Genome Sequencing.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORE89464.1}.
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DR EMBL; AQQV01000001; ORE89464.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1SII0; -.
DR STRING; 1317117.ATO7_06275; -.
DR OrthoDB; 9782445at2; -.
DR Proteomes; UP000192342; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000192342};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 299..584
FT /note="DNA methylase adenine-specific"
FT /evidence="ECO:0000259|Pfam:PF02384"
SQ SEQUENCE 994 AA; 112510 MW; B83123CFC11676CB CRC64;
MNNLSLLLEI LGYDTSRGWL PANEFDQIVG PVSALRRARD HMNVCGAFGT WQTLRRSDGQ
QRFTPFLFIA EAKDDDTAKT VVHRRVWSQG LAPFLIISTP KYVYISEGYH FSHSNWEQSV
KRVQWEQLKS GVDSNDRKVL TRFAANRLLS SVAWRDFTIN PSSRVDRRLL STLEALSCHV
TQQSGVSARS ANTLIGRFLY FYILHDRALI DEGWLAKFGA ESAFTQRNDN LNTKMAWEVF
DELDKLLNGS IFPLTKGERS QFSDADVRLL RDCIKLGDEP YGSLRQLNFF DFDLSCLQTE
TLSAIYEQFL KTEDAEKKRT EGVFYTPPFL ADFVLDRVED AVELNDSKRI IDCTAGSGVF
VVGAYRRIIE SLLQKKRETY LSAAKLRDTL TGSVFAIEKN PSAHAVTSFS LYLTMLDYVA
PRELNDCLHG QAEEPLFPHL AKHNIICSDF FTTSPPQNES QRFDIAIGNP PWQKLAEVTS
AEGIKNTTRF EAQVDANEAA EHAVWLLLDK YLRKDGIAAQ VVPTKSLVSP SAKRFPLQLA
QKVEVIGVVN LTHLRYQLFK NARQAASVVI LRNNEPAQSS TAWVLSPTRA HLPGPTDLGA
PWMIPYDPSQ IQKVHQRTLA KGGSSWFESI MLRPIDRHIR RYVADIVELN RVCSLKGFLE
AHKLNLARGG SPAQTGLTAA AICGADKNSA NDFRKFEGIH FISPLRQRTT IPELPYSGLA
SDWQKSINQA FIRRFSGHVL IIPRSLQGIA YVRAPLAFNS SLNALYFKKY PLTHEESGYQ
ERVLTAIGRY LESDVAQYLI AITGRLWMLD RTRLEKNDLL NIPLPFKDID DELINLLHDE
DQDRLSMALL KRFGFSQSMT EVVLEYSKFR KSFEDGQVPV FFASSPTNQD FSAYKNALSR
ALRSLCDESI DIHISPINAE TNTYRVSIQL DEKSDSRFFV SRQAGTADFF ECSALEHNDA
QTSVELVKPA EKFRWTIESA YTDGAKIIQT FLEE
//
