ID   A0A1Y1U6E5_9TREE        Unreviewed;       639 AA.
AC   A0A1Y1U6E5;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Peptidase M24, structural domain-containing protein {ECO:0000313|EMBL:ORX33572.1};
GN   ORFNames=BD324DRAFT_654028 {ECO:0000313|EMBL:ORX33572.1};
OS   Kockovaella imperatae.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cuniculitremaceae; Kockovaella.
OX   NCBI_TaxID=4999 {ECO:0000313|EMBL:ORX33572.1, ECO:0000313|Proteomes:UP000193218};
RN   [1] {ECO:0000313|EMBL:ORX33572.1, ECO:0000313|Proteomes:UP000193218}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-17943 {ECO:0000313|EMBL:ORX33572.1,
RC   ECO:0000313|Proteomes:UP000193218};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Louie K.B., Bewick A.J., Labutti K.,
RA   Haridas S., Kuo A., Salamov A., Ahrendt S.R., Lau R., Bowen B.P.,
RA   Lipzen A., Sullivan W., Andreopoulos W.B., Clum A., Lindquist E., Daum C.,
RA   Northen T.R., Ramamoorthy G., Schmitz R.J., Gryganskyi A., Culley D.,
RA   Magnuson J., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Widespread Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORX33572.1}.
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DR   EMBL; NBSH01000019; ORX33572.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1U6E5; -.
DR   STRING; 4999.A0A1Y1U6E5; -.
DR   InParanoid; A0A1Y1U6E5; -.
DR   OrthoDB; 869at2759; -.
DR   Proteomes; UP000193218; Unassembled WGS sequence.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01085; APP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR033740; Pept_M24B.
DR   InterPro; IPR032416; Peptidase_M24_C.
DR   PANTHER; PTHR43763:SF21; X-PRO AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF16189; Creatinase_N_2; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   Pfam; PF16188; Peptidase_M24_C; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000193218}.
FT   DOMAIN          10..132
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          347..563
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   DOMAIN          576..639
FT                   /note="Peptidase M24 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16188"
FT   REGION          271..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   639 AA;  71628 MW;  B1E686C09B558FE3 CRC64;
     MSTKSANDKL SALRSLMQEH NVGAYVVPSE DAHMSEYTAP VDQRREYLTS FTGSAGTAIV
     TKDEARFWTD GRYFLQAEKQ LGKEWILMKS GMTGVPTWQQ WLKNDLPAKS RIGMDPTILA
     HAEHSSLTKS LSEGNKSYIV AIDDNLVDDV WGTERHPRPS NPVIQLEDKY AGASVGSKLT
     KLRELLNQVG SPGIVVTQLD EVAWMFNLRG SDIAYNPVFF AYAILTPDDC NLFVNAKCLS
     EPIRDYLHKN NVSILDYEKV WPHLKTLGER TKESRAQKAK EEEEKGSTGP KEITLPDGEK
     IIKTDKVLVG KKTSWAVVRV LGEENVEVRR SFVEDEKAKK NATEIEGFRQ CNIRDGAALC
     RYFAWLEEEL SKGAKLTEYS AAKELENFRK QNEKFMGLSF STISSTGPNA AVIHYEATEN
     DTAVIDPNQI YLCDSGAQYL DGTTDTTRTM HFGTPTEEEK LANTRVLQGH IALDRAVFPK
     GTSGFVLDAI ARIPLWQDGL DFRHGTGHGV GHFLNVHEGP QGISPRPTTL DIALKEGMVI
     SNEPGYYADG KFGIRIENVF AVKRANTREN FGGKGYLEFE HFTMVPMQTK LVQHDLLAPI
     EKKWLNDYHA EVLEKVTPVL KSFGDDRALK WLERECKAI
//