ID   A0A1Y1UE91_9FUNG        Unreviewed;       698 AA.
AC   A0A1Y1UE91;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=DNase I-like protein {ECO:0000313|EMBL:ORX35824.1};
GN   ORFNames=BCR36DRAFT_375801 {ECO:0000313|EMBL:ORX35824.1};
OS   Piromyces finnis.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC   Neocallimastigaceae; Piromyces.
OX   NCBI_TaxID=1754191 {ECO:0000313|EMBL:ORX35824.1, ECO:0000313|Proteomes:UP000193719};
RN   [1] {ECO:0000313|EMBL:ORX35824.1, ECO:0000313|Proteomes:UP000193719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=finn {ECO:0000313|Proteomes:UP000193719};
RG   DOE Joint Genome Institute;
RA   Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA   Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA   Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA   Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT   "Genomes of anaerobic fungi encode conserved fungal cellulosomes for
RT   biomass hydrolysis.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ORX35824.1, ECO:0000313|Proteomes:UP000193719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=finn {ECO:0000313|Proteomes:UP000193719};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORX35824.1}.
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DR   EMBL; MCFH01000167; ORX35824.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1UE91; -.
DR   STRING; 1754191.A0A1Y1UE91; -.
DR   EnsemblFungi; ORX35824; ORX35824; BCR36DRAFT_375801.
DR   OrthoDB; 996872at2759; -.
DR   Proteomes; UP000193719; Unassembled WGS sequence.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProt.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR046985; IP5.
DR   InterPro; IPR000300; IPPc.
DR   InterPro; IPR048869; OCRL-1_2_ASH.
DR   PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR   PANTHER; PTHR11200:SF299; PHOSPHOINOSITIDE 5-PHOSPHATASE; 1.
DR   Pfam; PF21310; OCRL-like_ASH; 1.
DR   SMART; SM00128; IPPc; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193719}.
FT   DOMAIN          44..414
FT                   /note="Inositol polyphosphate-related phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00128"
SQ   SEQUENCE   698 AA;  80894 MW;  4ECD2F9485DBAAE8 CRC64;
     MTTTDENPFI HPLSSEITLN YRLSRECWIS KQLAIEQPKF TDLKKINIFI GTWNVNGRDP
     ECSLKGWLNS YKHKIPDIYV IGLQEMDLSK EAYIVSNNEK ENHWSEKIEE GINSLNKKYV
     KIASQQMVGI CVFVYVRKEL KKVISNVSTS FIGCGLMGIM GNKGASGIRM MIYDSYVCFV
     NSHLAADTMQ VQRRNEDYRD IAKNLQFPFI PPRDNINGFY NGTGFNKEQF YTENMLRFNI
     TSNKWLNNIC QENLKEKGNM KINFSIYDND ILFWFGDLNY RLNNNSDVIK EYINQGKIED
     LLEFDQLLIE KAKQVVFTDF YESKITFKPT YKYDIGTNTF DTSEKKRAPA FCDRVQWYKA
     SNALKPSEVS FSNKITIEDN EWIIPKNYNS YGELTISDHK PIISEFEIWV RKINTEKYSE
     IYSQLIKQLD HHENDRKVLS SYELVTSLDD NKTSLSFPWI SVKPSSNTIY PGESQTINIT
     LTVTTGISIK KIDEIIILKV KNGNDIFINV KSEIVPSLFG IPIETLCQIN RPLSYYPWDS
     ILELSNKKEL SEKTKELLEN EEISCIPKNL YVVIDFLIKY GRDEKYVFNN GNIIIKKSSL
     SDSYLNSLDN LTSMDSMDSA ISSISKMEKL SLYDYQSSES KTNLNEIIYK NYSLKAVKQK
     IAEIVKRQGK LPSINSMAEI LMKFLYEFPN AVVPYENF
//