ID A0A1Y1UQF5_9TREE Unreviewed; 1562 AA.
AC A0A1Y1UQF5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Phospholipase {ECO:0000256|PIRNR:PIRNR009376};
DE EC=3.1.4.4 {ECO:0000256|PIRNR:PIRNR009376};
GN ORFNames=BD324DRAFT_641172 {ECO:0000313|EMBL:ORX40300.1};
OS Kockovaella imperatae.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cuniculitremaceae; Kockovaella.
OX NCBI_TaxID=4999 {ECO:0000313|EMBL:ORX40300.1, ECO:0000313|Proteomes:UP000193218};
RN [1] {ECO:0000313|EMBL:ORX40300.1, ECO:0000313|Proteomes:UP000193218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-17943 {ECO:0000313|EMBL:ORX40300.1,
RC ECO:0000313|Proteomes:UP000193218};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Louie K.B., Bewick A.J., Labutti K.,
RA Haridas S., Kuo A., Salamov A., Ahrendt S.R., Lau R., Bowen B.P.,
RA Lipzen A., Sullivan W., Andreopoulos W.B., Clum A., Lindquist E., Daum C.,
RA Northen T.R., Ramamoorthy G., Schmitz R.J., Gryganskyi A., Culley D.,
RA Magnuson J., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Widespread Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798,
CC ECO:0000256|PIRNR:PIRNR009376};
CC -!- SIMILARITY: Belongs to the phospholipase D family.
CC {ECO:0000256|ARBA:ARBA00008664, ECO:0000256|PIRNR:PIRNR009376}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX40300.1}.
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DR EMBL; NBSH01000002; ORX40300.1; -; Genomic_DNA.
DR STRING; 4999.A0A1Y1UQF5; -.
DR InParanoid; A0A1Y1UQF5; -.
DR OrthoDB; 335467at2759; -.
DR Proteomes; UP000193218; Unassembled WGS sequence.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006654; P:phosphatidic acid biosynthetic process; IEA:InterPro.
DR CDD; cd01254; PH_PLD; 1.
DR CDD; cd09138; PLDc_vPLD1_2_yPLD_like_1; 1.
DR CDD; cd09141; PLDc_vPLD1_2_yPLD_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR016555; PLipase_D_euk.
DR InterPro; IPR015679; PLipase_D_fam.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR18896:SF76; PHOSPHOLIPASE; 1.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR Pfam; PF00614; PLDc; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR PIRSF; PIRSF009376; Phospholipase_D_euk; 1.
DR SMART; SM00155; PLDc; 2.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50035; PLD; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR009376};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW ECO:0000256|PIRNR:PIRNR009376};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963,
KW ECO:0000256|PIRNR:PIRNR009376};
KW Reference proteome {ECO:0000313|Proteomes:UP000193218}.
FT DOMAIN 659..686
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 957..984
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1126..1158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1189..1274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1376..1494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1147
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1562 AA; 174409 MW; 1280F2CB19D50217 CRC64;
MEELKDEMGN SPERLPGVKK EEPPGPRTVI ELNTRTPHQH YHRQFRSLGQ GKTPILKITP
DGEGEYPPGE TPQPSRQSSF HRPNRQSIEE RPSNEADGHW TSALDKAASS SPTSTPQRHH
DKAMNARFSA FRESRFSETD GDHEHELAQK RWSMLRARVL PSRHNSNGPT PGPGKVSALS
TTAINTLPVT TELFAGQLPV MMLKTWIDRD EDGRRAVPVL LGNMRFRVGD SVGVGAGKET
GKEMFKVECE YGDGAVKWVI YRELRDFLSL HANYKAANFG TSVGGLRSSR RVEIPEFPKM
SIPYFSRSHG KDQAQMAREA LQKYLVELIR AVIFRPESNR LCRFFELSAL TVALAPHGGF
QGKAGFLMIP GSNASRRANQ PGLTPTSWIH NRSPKWLIVR DSYFVATEGP EDTEFYDVFI
LDQDFAIERP KRAYRHGLHL VTGKSSIKRS HKHSATDEIE VDPENPLATE IAINSGEGKG
PNPHTLGDDG QESYASQHTF FIVSSQRKLK LQARNARHMH QFIVSMERIA AQCIWTSRNR
FDSFAPLRVN VAAQWLVDGR DYFWNLSRAM NMAKDRIYIH DWWLSPELYL RRPGDERYRL
DNLLKRKAEE GVKVYVIIYN EVSDKTTPVD SLYAKKTLTG LHHNIMVQRS PSHFQTGTFY
WSHHEKLCVI DETIAFMGGL DLCYGRWDTS QHVLTDEDHT EPDGPNGPVW RGKDYANERV
AEYANLDKPF EDMFDRTKVP RMPWHDVGLQ IVGQPARDLC RHFTQRWNLL IRTKNHTRRM
PFLLPPPDFT EGELGDLKLQ GTCEVQICRS VGPWSMGTLT KIEHSIQNAY CKSIQLSEHF
VYIENQFFIT STVVDGIQIH NGIGDALVER IIRAHKEKTT WRACIVIPLL PGYTYPLDSA
EASSVRMILE CQNRTIARGA GSIFSRLRKE GIDPDEYITF FSLRTWSKFK SGVLTTEQVY
IHGKTMIVDD RLVLCGSANI NERSQRGDRD SELVAVIRDT DMIDSKMAGK PYKVGRFSHT
LRMRLMREHV GIDVDSIEED QLMSREPIAP EDEIETWDPD HQQQDKDELT EGITTVSKRT
AMERMRRTVG NAMASVTKGM SENAVDNVGR AADKIIHPIA VVKDHAFVDP RNDTPGEKSE
RQDFSHGGGK TKGFASSIVP TLEEKTIFDR RPSATHANGK PLFDLIEESE NQQQSAGRPE
EAEVPADAKQ NESVLEENDP SASAHAKAKA PKIHGNPHEK ELFGVPANAV DGDDAPPNDN
TSRSEGTSDE KRAIGARQTL RKHLSAKTAM TPWSMPTPTP KINPNRFQDP LDETFWKDMW
VAVAVHNTEI FRKVFRCIPD DLVTTWAAYK AFANHAEKHN KAPEDVAENK NEEPVKVVHD
GPGTHGSGGG GSGGGAKSET RGADIPEGGG GGGGVGGGGG GKEEDGPTSR MEGGLMGKLG
AKDTTSNVDP GQKVDNPSGF GEKKPDGGGD GAGGGGDAGE SLGKRVPSGP QEPWAQWERE
EMEELLNEVR GHLGEFDKRV HYTNAIADTP SLSPPSVIYP QRFLEVEDQI GNLLFQLAAV
QK
//
