ID A0A1Y1W3I3_9FUNG Unreviewed; 1698 AA.
AC A0A1Y1W3I3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sec63-domain-containing protein {ECO:0000313|EMBL:ORX68028.1};
GN ORFNames=DL89DRAFT_269171 {ECO:0000313|EMBL:ORX68028.1};
OS Linderina pennispora.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Linderina.
OX NCBI_TaxID=61395 {ECO:0000313|EMBL:ORX68028.1, ECO:0000313|Proteomes:UP000193922};
RN [1] {ECO:0000313|EMBL:ORX68028.1, ECO:0000313|Proteomes:UP000193922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12442 {ECO:0000313|EMBL:ORX68028.1,
RC ECO:0000313|Proteomes:UP000193922};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX68028.1}.
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DR EMBL; MCFD01000011; ORX68028.1; -; Genomic_DNA.
DR STRING; 61395.A0A1Y1W3I3; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000193922; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProt.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041094; Brr2_helicase_PWI.
DR InterPro; IPR048863; BRR2_plug.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF21188; BRR2_plug; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF18149; Helicase_PWI; 1.
DR Pfam; PF02889; Sec63; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193922}.
FT DOMAIN 445..605
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 628..796
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 51..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1698 AA; 189453 MW; 29B401A750D0F7E2 CRC64;
MGEELTKEQQ KLYQYAGNSN LVLQSDRSGL ARRGERGKEV ESLYGKIDAR DMGANVRHEA
PPKAPTQGKT RREQRALRTN YGYTNILAAT EDIEGVAYRP RSRETRRVWE MILAQARKYL
GDQAPEVLMS ATDEALAVLK NDNVREREKK KQTEFSVFIQ LARQITDYED EPMEVDAGRP
DAQSGMAVAG QFVVDGESSG SDSEDDEDRK APEDHGSDVG SVQGDDEAGG YRTVIHGFGK
DAADDGSDTE MVDAPDRLPP RSIDAFWLQR EIGKHFPDHM AALRLLANRR LAAGELENEL
AELFDYDHFE TVQVLVQNRE LIAEDDSQQK TGIEEEMREN GLGWIAQQQP PQQPPQQRQS
ASSQDVVMEE AKANEPRDFE PRQTIDLAEL AFTQGGHLMT NEKWVPPKGA EKEIRVPAPE
RPPPAGDDEP IWSRTAFPGA KELNRVQSRA DDNMLICAPT GAGKTNCAAL TMMRTIGQFR
DSATGEINVD QFKMALVAEV AGSFSKRLAP LGISLTKQQI AATQLIVTTP EKWDVITRKG
GEGSYTQLVR LVIIDEIHLL HDDRGPVLEA LEQTQQRVRL VGLSATLPNY EDVATFLRVP
RDRALFHFDA RFRPCPLQQE FHIKRLERMD QVCYDKVKKH AQGSQVLVFT ESQTGLAILE
DAAESTRDQA LKELLPFGFG CHHAGMSKAD RGQMEDLFAN GRLKVLVSTA TLAWGVNLPA
HAVIIKGTQL SPQDVLQMLG RAGRPQYDTF GEGLRYYLSL LNQQLPIESQ LMSRLADALN
AEVALGTIRS RNDAVDWLGY TYLPSVYGVP GGEIDEDPAL VGRPAVELAR SAMVQLAHRD
IDILRFRLIP VRAEERRVPA KINVLLQAHI ASLGLTGFAL VSDMVYVTQS AGRIFRALFE
LCLPHRVLGW CKQFGRACPT DLVRSVERKP FPWARYLGEL VGSPKAGRLL HGLVHLVPRL
EVSAHLRLTP DFRWQDAFWI WRMLHSELFV LKKLYVGQEH PLPPQYFVCT RLAVSFNCMT
LSSSAFTRLP SRQCSAPRRA PARRWLGSWR CCGFSSTRRC GRELTRWRGH EHMSGSSGLH
RCRAERLWRF CQATWPGDLK RIENAHIIWR ARQHHAVREI GLVIADELHC GSDYGAGADL
VGDQLAATYE VVVSRIERPI RIIALSVPLA NARDVAAWIG APPSAVFNFS PAVRPTSTIP
HFASRMAALA APTYRAVCGD PSREPAIVFV PSRRQCRVVA GELLTLAAAD GASIIESAIG
RFLAYGVGYY HEALTDADRQ TVTGFRETCW ALDSVHAQTV HRYVDYSIPD VLQMMGRASR
PGIDTKGLCR ELYKKFLYEP LPLDEIQEAV DYLTWTLMYR RLGTTHPASI RLPCVTLDDD
EVGVSATNLG IISAFYQIRY LTVEMFALSL AAKTKLRGVL DIVSAADEFE ALPIRHREAH
VLNKIARRCP LALPSTSNDS DDGRWNSPRV RTHLLLQAHF SRLALPADLA ADQAWVLARV
MPLLQALVDA PALASMELSQ MCVQAMQVPH LGGSERLQMC ESMQVDSVFA VMDMEDEDRA
NQVAEVAAYV NRYPNIEVEF EVAGEVHANG IVSLVLSLDR EWDEEEEGDI PGPVIAPFFP
YARAEGWWVV IADGQTLVNV RKISVGKELQ RTIKFAAPEV AGQRNLKMFL MCDGYLGCDQ
ELDVELDVLP PEEESDSE
//
