ID A0A1Y1W4L7_9FUNG Unreviewed; 379 AA.
AC A0A1Y1W4L7;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Alpha/beta-hydrolase {ECO:0000313|EMBL:ORX68114.1};
DE Flags: Fragment;
GN ORFNames=DL89DRAFT_208844 {ECO:0000313|EMBL:ORX68114.1};
OS Linderina pennispora.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Linderina.
OX NCBI_TaxID=61395 {ECO:0000313|EMBL:ORX68114.1, ECO:0000313|Proteomes:UP000193922};
RN [1] {ECO:0000313|EMBL:ORX68114.1, ECO:0000313|Proteomes:UP000193922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12442 {ECO:0000313|EMBL:ORX68114.1,
RC ECO:0000313|Proteomes:UP000193922};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX68114.1}.
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DR EMBL; MCFD01000010; ORX68114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1W4L7; -.
DR STRING; 61395.A0A1Y1W4L7; -.
DR OrthoDB; 5474043at2759; -.
DR Proteomes; UP000193922; Unassembled WGS sequence.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR PANTHER; PTHR11005:SF103; STEROL ESTERASE TGL1; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ORX68114.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193922}.
FT DOMAIN 6..83
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT REGION 32..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 160
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 331
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 358
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ORX68114.1"
FT NON_TER 379
FT /evidence="ECO:0000313|EMBL:ORX68114.1"
SQ SEQUENCE 379 AA; 44299 MW; 269A723A6165C2B0 CRC64;
DFNSFAEIME FWGYPYEDHL VETRDGFLLG THRITGPRGG PVQQHQQHQQ HQQHQQPPQS
SGGKPVVLFW HGFMLNSECF VCHPDWINIL PLRLAEAGYD VWLGNSRGNK YSYKHMKYTP
DQKRFWNFSI DEIANIDVPT TVDYILKETG AKTLTYIGFS QGSAQMFMTL SRNKELNYKV
EHFIALAPAS TPRGFHNRVV DYFIRATPHM LYLLFGRRRA MKLVYFWVNI LPRDIYVAAL
DFCVNLLFGW RTRNMSQETK HIVYWHLYSY TSVKAIVHWM QIIRCGELQM YDEDPPAYPQ
GYTMGPLTHW NNTYPLKRIN TRLSLFYGGS DSLASVDTLV EELSIVPEEC MRFSHYEHLD
FLWADDVGTL VYPKVLALL
//
