ID A0A1Y1WBE8_9FUNG Unreviewed; 1646 AA.
AC A0A1Y1WBE8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Myosin-2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DL89DRAFT_292318 {ECO:0000313|EMBL:ORX70695.1};
OS Linderina pennispora.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Linderina.
OX NCBI_TaxID=61395 {ECO:0000313|EMBL:ORX70695.1, ECO:0000313|Proteomes:UP000193922};
RN [1] {ECO:0000313|EMBL:ORX70695.1, ECO:0000313|Proteomes:UP000193922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12442 {ECO:0000313|EMBL:ORX70695.1,
RC ECO:0000313|Proteomes:UP000193922};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX70695.1}.
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DR EMBL; MCFD01000005; ORX70695.1; -; Genomic_DNA.
DR STRING; 61395.A0A1Y1WBE8; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000193922; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 5.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 6.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000193922}.
FT DOMAIN 79..779
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1308..1559
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 654..676
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1091..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1611..1646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 945..1082
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1611..1625
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 172..179
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1646 AA; 186119 MW; 961834C863875BFF CRC64;
MSSPSTEASL AELKVYAKKA WVQATLTEKV VDEASRTVKM TFEGNDEDAP QTYHFEATFD
ELLKKLKGLP PLVNPPLLEG IDDLTNLSHL NEPAVLHNLH VRYGMHNIYT YSGIVLVALN
PFARVPLYSQ DILEAYAGRM RGELEPHLFA ISEDAFQGMV RDRKNQTIIV SGESGAGKTM
SAKYIMRYFA SAHEDGSSSN DSSGISKVEE QILATNPVLE SFGNAKTTRN DNSSRFGKFL
EIRFNERHAI EAAFIRTYLL ERSRLVYQPT IERNYHIFYQ LLAAVPEDMR DKLGLTNATW
ETFHYTSQGG SGEIAGVDDA VEFKITSDAL SVIGVSNESQ KLIYTLLSAL LHMGNLEIGG
SERMGASIKD DNAACNKVVE LLQIDGTLFR KWLTKKQIVT RSEKIVSNLT VVQSQVVRDS
VAKFIYAHLF DWIVATINAS LVGSAAGDPA SFIGVLDIYG FEHFEHNSFE QFCINYANEK
LQQNFNRHVF KLEQEEYQRE QLANWTFVDF QDNQPCIDLI EGKLGVLALL DEESRLQQGT
DKTFAEKLYR QFASSPKPQP ETPSAFFRKP RFGSDKFTIR HYAHDVTYES EGFIEKNKDT
VPDEIQNVLK ASTNSFLKEI LVEPEPEQQP APKGRLSVRA ARKPTLGTVF KHSLVSLMET
IEATESHYIR CIKPNEAKAA WQFDAPMVLA QLRACGVLET IRISCAGYPS RLLIPEFIHR
YRVLLPSEVS SQANSMEDVR ALAVKILDSA FQESDRYQVG LTKVFFRAGM LALVEKLRVE
RLNSAATKIQ CLVRGHQQRT KFLKMRKAAR VIQLGVRGYL ARRELQKRRN TRAAVVIQSA
VRAYLARTNY ARERHAIVRL QAMVRGKIAR KQTLALRQVH AASVIQKHVR GHQKRSAYLH
QRDLVVKMQS NVRARAARRE LKGRKEEVRS AAHFQEVTYK LEGKLMELTR QLQTQRNESK
QLSIQLAESE ARSAQLAEKL AGSQQESREL RDQQEDKIRL ATEELTRQVA EVTAAKAAVD
EKCKQLVDQV AATHKELNAV RAEAERERGE SMTAREQLEK KLEELEAELS ASKTQLADAR
AQHQQQMLIY QQQHSNEQPS SIKRSDTSGS RWKAAANYSA TGYEMADSAT PPHPLPHVGG
AVLPNAHANA HPISPVEDVQ RRPHSVDTAR QASARALESV ANKRSTIGGD EGRTLAKMLG
SLGAFGAGAI AEEEEHPAFE LHSEDEVRDM LESDDNLITE VLNELIGDLQ VPLPNLDAEY
SQPDLLFPAH LIGLCVIKMF QYNLSRRIDR LLMSSIARIQ KKTAAFESDY TSAFWLSNVF
ELLSIIKTSM TEHQSSTYEY AESERAMNEG MQYLESLLSD IYFGWIRDLQ KRFGKLIIPG
VVESEALPGF TANDSSFFNR LMGTGPRESP VKIENVLSFF NHIWRTMEFY FVNPAIMRQI
MSELLCNIGV TAFNNIIMRR NFCSWKRGMQ IQYNLTRIEE WCKTHNVADS SRNLDRLLQL
VKLLQLQKSS EQDIDIMFEV CDLLNPAQIK KLLSIYAVSD YENPIVGPVM TEVTRRAAST
EKSDNILLDT NDLTDQVLYL TARKVPAIET YIPPEFKMPR VRALVDSQTD VAYDDDDEEY
GDEDDEVGDY GHHPVDRYSE QTLAYN
//
