ID A0A1Y1WUJ8_9FUNG Unreviewed; 1065 AA.
AC A0A1Y1WUJ8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Rap-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR32DRAFT_283391 {ECO:0000313|EMBL:ORX77229.1};
OS Anaeromyces robustus.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC Neocallimastigaceae; Anaeromyces.
OX NCBI_TaxID=1754192 {ECO:0000313|EMBL:ORX77229.1, ECO:0000313|Proteomes:UP000193944};
RN [1] {ECO:0000313|EMBL:ORX77229.1, ECO:0000313|Proteomes:UP000193944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4 {ECO:0000313|EMBL:ORX77229.1,
RC ECO:0000313|Proteomes:UP000193944};
RG DOE Joint Genome Institute;
RA Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ORX77229.1, ECO:0000313|Proteomes:UP000193944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4 {ECO:0000313|EMBL:ORX77229.1,
RC ECO:0000313|Proteomes:UP000193944};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX77229.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MCFG01000258; ORX77229.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1WUJ8; -.
DR STRING; 1754192.A0A1Y1WUJ8; -.
DR OrthoDB; 25782at2759; -.
DR Proteomes; UP000193944; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd09358; LIM_Mical_like; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000193944};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 7..67
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 693..911
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 260..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 931..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..950
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1065 AA; 120551 MW; F070F5715253F95B CRC64;
MASNGNGVCC ICSKAVYATE LMVVDEREYH KGCFRCNVCK RPITITSYNS YNGEIYCKAH
KPSIDKNPEP LRHGYDCATM PASLKHARNQ TAPPLVFNKN LQKVYEGDIK SPMSENMYSL
KNIFEKNDLS QSAPTTPQSP TFSSSPTTLE RIEILKKEIQ QNNNSSSEIL YTRASLSKTS
SLRLKKKNPL NQDGSTHVEK MEKINKLLDE IDENWNEFEK TNAEYMNKHH SRNSSFSSMK
EAKNSELTKS DSFKDCIIKE ENEDESRKEN ENNEIEQDLT DEDINKCEKE MDDTLRNIDS
YISNYYERKN ETVSTDGSIE SFLEEYSIDS SIKPMTKEKE NSNIIGGINN IFKKNSEKLN
SNTFTGNVST KSNILWIRAS TDYKYDKLAV ASKKQNHYKK YLTSTTLQDY LNIAFETKIP
DTRSLQDVCK CIEQYSSEIK HGCETSTQLN NNRPLIESVA SPLKFLIDSL NSLYIKLRGV
INTIKLTKFI NLLASIEDIL IKEGFQHIVE VQTQEEYSNL LINACEIITN YSQIMLFKYK
QFKRKVNVFL RDTFRLEITT ISDDVVFSYA ECTLDRVNAD AKLYRNAFVD QEHRNYVGNQ
QCINGPFIIS LRKLKKIQSS DTKSEDNAAY QAIVRIKDTP EIIVLIPSVT ARSQAKLRSS
SSWKSVLQAI HPEINITAVC KVKEKDKVFQ KRLMDLDEFQ CVSKYKFGIL YAKDGQTTEE
QMFNNENGSP AFKEFLDILG DTVELKGYTG YAAGLDVQYG NTGDTTVVTK WRDYDVTFHV
STMLPYDKDD PQQIQRKRHI GNDIVCFIFL DGSEAKFDPG TILSQFLHIF IVVQPLQPEE
SLGIGYRVTI VSKTDVPIFG PPLPPSGIFH NTSALRHFLL AKGINGENAA YLAPKFSKPQ
LRTRGALIED LVKDYYEPST INSSVSLSNM ASAGGISQSP TNNTIRSLDS DNNAKIEKRS
TFNTTSMTPT VTIIEEDGEN NENNLHLKKT LSTSNINDDN DDGCDPKLER YDSSESLKQC
QKIYRSQTSV SSDNADKKKS LSSLFTSISN LGKGKPHGSI PPPAK
//
