ID A0A1Y1XDH7_9FUNG Unreviewed; 752 AA.
AC A0A1Y1XDH7;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR32DRAFT_142506 {ECO:0000313|EMBL:ORX83783.1};
OS Anaeromyces robustus.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC Neocallimastigaceae; Anaeromyces.
OX NCBI_TaxID=1754192 {ECO:0000313|EMBL:ORX83783.1, ECO:0000313|Proteomes:UP000193944};
RN [1] {ECO:0000313|EMBL:ORX83783.1, ECO:0000313|Proteomes:UP000193944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4 {ECO:0000313|EMBL:ORX83783.1,
RC ECO:0000313|Proteomes:UP000193944};
RG DOE Joint Genome Institute;
RA Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ORX83783.1, ECO:0000313|Proteomes:UP000193944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4 {ECO:0000313|EMBL:ORX83783.1,
RC ECO:0000313|Proteomes:UP000193944};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX83783.1}.
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DR EMBL; MCFG01000065; ORX83783.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1XDH7; -.
DR OrthoDB; 1331864at2759; -.
DR Proteomes; UP000193944; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193944};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 467..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..704
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 424..457
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 468..708
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT DISULFID 447..456
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 752 AA; 85240 MW; 4EDCC02EE795652F CRC64;
MFASDIIIEY TPDKSTDFIE QLCTANVIFG TIDSIITNIG DSENTYRNVP FDAIKEESPL
ARAEWIKFIA LFYNEEKLAE DLFNLLEEDY NELIKIANAK RTSSVKTIAW VSYDKSQKTW
TYHTNDFYKI LTQDAGSKLF TSYSKDSSFL NNVKNVDFII DISESGTNSD ITDFFKNAGL
DTGKCNDYNF CKNNHIMKFD KRENKDHFNA WDEYLLPMAN VLLIELQNLV SPEVFNNDDT
NIWYHSIYLR SINDNKFDTY TYEDCYDINS SVIYERFATT ENLNIQTLSG EWIPYSFMLG
IKTYNGTNFK SKNDESTADG ALFITVIIVD RNNTGIISET STIYGKKRWR CNLSNSTCSI
PANEFQVIGH DGDYTLNFTI IENENWQFDT LINAYASVNI TINKCNTTEY KYKDITNTLL
ESCYKPDCPG GCAHLGSYCE DLNKCKCADN WTGPNCNDKV KFVVPKWLQY MFFIIGITSA
VLCCILILML YLRRNLQHVR SSSPLFLMIM TVGAVCNSGT IILESIDDSI PICILREWCK
YIGFSLMVGA LIVKTIRISL IFSGKKIGGS QLADKRLIVY LFGILIPFII LLIIWTTVDK
AKIITDERSD KEFQKCDSHT TSIIGDVFLF AILFWAVHAA YTARNAPSAF NETKAIVLST
YVYFIIEVLV IVLQNLGSFD PTVSMTINCL ATLVSTWCCL LFILKPKMKN VTSQMTPSQY
SSTSHSQSEA YNSTVGTASM GTTSIGVKSG RL
//
