ID A0A1Y1XGY9_9FUNG Unreviewed; 1051 AA.
AC A0A1Y1XGY9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=BCR32DRAFT_276638 {ECO:0000313|EMBL:ORX85007.1};
OS Anaeromyces robustus.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC Neocallimastigaceae; Anaeromyces.
OX NCBI_TaxID=1754192 {ECO:0000313|EMBL:ORX85007.1, ECO:0000313|Proteomes:UP000193944};
RN [1] {ECO:0000313|EMBL:ORX85007.1, ECO:0000313|Proteomes:UP000193944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4 {ECO:0000313|EMBL:ORX85007.1,
RC ECO:0000313|Proteomes:UP000193944};
RG DOE Joint Genome Institute;
RA Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ORX85007.1, ECO:0000313|Proteomes:UP000193944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4 {ECO:0000313|EMBL:ORX85007.1,
RC ECO:0000313|Proteomes:UP000193944};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC clathrin to receptors in coated vesicles. Clathrin-associated protein
CC complexes are believed to interact with the cytoplasmic tails of
CC membrane proteins, leading to their selection and concentration.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX85007.1}.
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DR EMBL; MCFG01000042; ORX85007.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1XGY9; -.
DR STRING; 1754192.A0A1Y1XGY9; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000193944; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF13; AP-2 COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 2.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000193944};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 817..917
FT /note="Clathrin adaptor alpha/beta/gamma-adaptin appendage
FT Ig-like subdomain"
FT /evidence="ECO:0000259|SMART:SM00809"
FT DOMAIN 939..1050
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
SQ SEQUENCE 1051 AA; 120276 MW; 442D459F89A31C62 CRC64;
MNSKKTSDAK YFQRGKIQEL KAELKSEKKD PKYTRKKNVL KKIVANMTMG NDMSPLFPDV
LVCMDIPVLE IKKMVYLYLI HYARNKPEMI LMALKSFTKD VNSNNPLIRA MAIRTMGYMP
ADKIIGCLGK PLHDCLQDRD PYVRKTAALT VPKLFMDDPI LVEREGYLNQ LKDLLNDSNS
TVVASAIAGL IEIADRSEKF DLSINFNLAN KLLTAMNDCT EWGQTYILEA MMFHVPQENQ
DAELLAERIV PRLQHANAAV VLTSVKVIIY LMNYMNNEEV VNNLYKKLGP PMVTLLHSGY
EIQYVALRNI LLIIQRRPDF LKNELKVFFC KYNDPIYVKL AKLEIIIRLT NIYNVGQVLS
ELEEYSSEVD VGFVRKSVRS IGRCAIKIPE ATDECIDVLI RLIHTKVDYV VQEAVVVIRD
IFRKYPNRYE SIIGILCENL DSLDEPEAKA SMIWIIGQYS DRIQNADELL DNFLETFKEE
TTEVQLSLLT AIVKLFIKRP TVGQALVPKV LKWATEEVDN PDLRDRAYIY WRLLSSDPVA
AKAIVLSERP AITTEVEDMD WNLLDDLLLN ISSLASIYHK PPSNFITGIK SRKLIQSPAL
NPNIHMQQQK TYNFDDDDNQ NIYNNVSNPY AMNDVQPMNS NQIDLLEFEN ADQNNQYVES
PQIDTSTDIS AKSGDDTFKV KENMTPTNFG SGTTFKINND LLGLDMNVTE PNQNMNNNQF
NNMNFMNGNM NNMNMNNMNM NNMNMNNMNN MNMNNMNMNN MNNMNMNNMN NMNMNNMNNM
NNMNNMNFMN NNMNPNVNLI TDGMNNININ NQNNNINDSY VPDKSTFLSS QSGNGMQIIG
TFARRQGQMQ MDLVFNNLSQ QPLSGFAIQF NKNSFGITPA SSLNIDGPLN PNDSSETVLN
LRKDGPVQQM TPINNLQIAV KNNTGIYYFQ TLIPIHILFL ESGKLEQEEW FKNWKDDSLK
EYKYNIANLN KYAEIKEITD KLQINNVFCI AERYVNNMNV LYLSVKLEQG IVFVMEMLVD
QPLRNVILST KTPAASLITP FQKAIEDILR S
//
