ID   A0A1Y1XY97_9PLEO        Unreviewed;      1286 AA.
AC   A0A1Y1XY97;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Pre-mRNA-splicing factor {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=BCR34DRAFT_595073 {ECO:0000313|EMBL:ORX90723.1};
OS   Clohesyomyces aquaticus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Lindgomycetaceae; Clohesyomyces.
OX   NCBI_TaxID=1231657 {ECO:0000313|EMBL:ORX90723.1, ECO:0000313|Proteomes:UP000193144};
RN   [1] {ECO:0000313|EMBL:ORX90723.1, ECO:0000313|Proteomes:UP000193144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 115471 {ECO:0000313|EMBL:ORX90723.1,
RC   ECO:0000313|Proteomes:UP000193144};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORX90723.1}.
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DR   EMBL; MCFA01000519; ORX90723.1; -; Genomic_DNA.
DR   STRING; 1231657.A0A1Y1XY97; -.
DR   OrthoDB; 7041at2759; -.
DR   Proteomes; UP000193144; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   CDD; cd17935; EEXXQc_AQR; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR048966; Aquarius_b-barrel.
DR   InterPro; IPR048967; Aquarius_insert.
DR   InterPro; IPR032174; Aquarius_N.
DR   InterPro; IPR026300; CWF11_fam.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF5; RNA HELICASE AQUARIUS; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF16399; Aquarius_N_1st; 1.
DR   Pfam; PF21143; Aquarius_N_2nd; 1.
DR   Pfam; PF21144; Aquarius_N_3rd; 1.
DR   PIRSF; PIRSF038901; AQR_cwf11; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000193144}.
FT   DOMAIN          42..428
FT                   /note="RNA helicase aquarius N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16399"
FT   DOMAIN          510..673
FT                   /note="RNA helicase aquarius beta-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF21143"
FT   DOMAIN          721..812
FT                   /note="RNA helicase aquarius insertion"
FT                   /evidence="ECO:0000259|Pfam:PF21144"
FT   DOMAIN          825..1121
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1132..1286
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          768..812
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        774..790
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1286
FT                   /evidence="ECO:0000313|EMBL:ORX90723.1"
SQ   SEQUENCE   1286 AA;  147079 MW;  9642A9F1EEE8A7AF CRC64;
     MEDVTYGDGR GAQHAATTAQ TSDFNGLHAR PTIADLHGEN HFAQAAQKHW LSAKKPPKVR
     PQVVKEEIWE ELEKCDFAYS SLLVLENLQL LERYLWPGYT EDASNHHHLL LALMANVKRR
     ENLTSWEHFA SSPENFSLFF RRILSMTVDP SHPTRIRTQL IAFIIGAFQS LDSGVVRKEC
     APLVSISIWQ NLHSDAARDD QFEQEPKLRK AWRAAAKRFD AADDELKARL RFERSWLYTL
     TLDFFDRLYN SARDTARENL AYCERFVELL TDLQSQLPTR RYVDSLLRDL NVLPAIRLSP
     MYTDEDNGLF RDLFNLLSHY TFFPIQDQTG RQLSKLEYDQ EHYAQLAKLQ RVGYAAFKEQ
     LTLLALSHYG SVGSRDELEG HLRTLDDAEL IELCSLMGLR TEYPKTSFLV QDRPFFTEVL
     VSIHEQRPTF KDIIREMPIL PTERILYEAT FLRNESYNGS RPLAIPKLNL QYLTMGDFLW
     RSFILYRCES FYGIRKDMEE VVKRMQPRGK GVSAKFTGFS RMAIPISKPA IVDVAPSRVG
     EEHPAHVRAE VILDVARLQH PVRKEWEALR SDDIVFLLAV EGADDEELSK GYSEQSGGER
     LGLRKLRCAR VVMVQDENGK PLREQAHTDG PPPRARQRRL ILHLDAKQYQ EDMDRVAQGR
     PDIYESINLV VRRRGRENNF LPILDSIRRL TLSDIPAPAW LQDVFLGYGD PASATYKRLS
     NRLNAIDFRD TFLDWQHLIE SLPGKSIEPH EDMQSSFGPP YVVSFPAAEP ESAPLRPSKK
     RRRDQVEVAQ PVHESLHVAT YKPPNTGPYP GDAPKLNTVR FTPAQIEAIT SGTQPGLTIV
     VGPPGTGKTD VATQIISNIY HDFPDQRTLL VAHSNQALNQ LFQKIVALDI DERHLLRLGH
     GEEELETEAS FSKHGRVESF LERREWYLAE VDRLAKNFGA PGAHGSTCET ADYFNLVYVK
     PAWSGYWDNV QSPDFSVEQI VAAFPFKHYF ANAPQPLFPP NAPREDVLDV ARGCYRHVEK
     IFAELEDIRP FEILRNPRDK ANYLLIKEAR IIAMTSTHAA MRRQEIASLG FHYDNVIMEE
     AAQITEIENF IPLALQNPQD GELPLKRIVL CGDHLQNSPI VQNLAFRQYA NLEQSLFLRL
     VRLGVPTIML DQQGRARPSI ANLYKWRYPK LGNLPNVLNA PAFQQANAGF RYAFQFIDVP
     DYKGKGEMEP TPHFIQNLGE AEYAVAVFMY MRLLGYPASR ISILTTYAGQ RALIKDVLGH
     RCKSNRLFGM PRMVATVDKY QGEQND
//