ID   A0A1Y1Y6R1_9FUNG        Unreviewed;       421 AA.
AC   A0A1Y1Y6R1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=P2X purinoceptor {ECO:0008006|Google:ProtNLM};
GN   ORFNames=K493DRAFT_338160 {ECO:0000313|EMBL:ORX93683.1};
OS   Basidiobolus meristosporus CBS 931.73.
OC   Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC   Entomophthoromycotina; Basidiobolomycetes; Basidiobolales; Basidiobolaceae;
OC   Basidiobolus.
OX   NCBI_TaxID=1314790 {ECO:0000313|EMBL:ORX93683.1, ECO:0000313|Proteomes:UP000193498};
RN   [1] {ECO:0000313|EMBL:ORX93683.1, ECO:0000313|Proteomes:UP000193498}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 931.73 {ECO:0000313|EMBL:ORX93683.1,
RC   ECO:0000313|Proteomes:UP000193498};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the P2X receptor family.
CC       {ECO:0000256|ARBA:ARBA00009848}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORX93683.1}.
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DR   EMBL; MCFE01000227; ORX93683.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1Y6R1; -.
DR   STRING; 1314790.A0A1Y1Y6R1; -.
DR   InParanoid; A0A1Y1Y6R1; -.
DR   OrthoDB; 1383335at2759; -.
DR   Proteomes; UP000193498; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015267; F:channel activity; IEA:UniProt.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR   Gene3D; 1.10.287.940; atp-gated p2x4 ion channel; 2.
DR   PANTHER; PTHR10125; P2X PURINOCEPTOR; 1.
DR   PANTHER; PTHR10125:SF31; P2X RECEPTOR E; 1.
DR   Pfam; PF00864; P2X_receptor; 1.
PE   3: Inferred from homology;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193498};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          374..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   421 AA;  47355 MW;  875785B5C802ED42 CRC64;
     MLSPVKNWWK RVDLDDLLGY DTFKVVHVRD RRLGFTFHGF QIAIFAYIIY SVIHNQLYLK
     KESPVPGAIR VSLLEPTGEL QTSPYCQQKP CVFWGANQIL YDPGDQGATF LTTRISTKVF
     PAREGCDFQL PTNAACRYNL QPSTVSPEYY ITDLDRYTLM IEHSVRGTAT GISIRNGEMS
     GRLLITKANN PYYQNETELH FSPQTRPPRV PGDIITVGQL LRASGAVLDA PSDAPGADQA
     KGETYRSSGI VLSVVIEYDN DGSTNFKYSY SANYIKGNEF KVEETIFNPT DGSITELNRH
     GIRIVFSQTG NIGKFDFMSL LTNLVASIAL LKTATLLVEI FMLKFLPQRK MYYEAKYELT
     EDFDDLRKRR NGEDIDLEGR KKPTTLGPGV EVTQPSPCHT HFSAEPLVEH RDDHVGPSKA
     V
//