ID A0A1Y1Y8S1_9FUNG Unreviewed; 2186 AA.
AC A0A1Y1Y8S1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=ARM repeat-containing protein {ECO:0000313|EMBL:ORX94275.1};
GN ORFNames=K493DRAFT_352634 {ECO:0000313|EMBL:ORX94275.1};
OS Basidiobolus meristosporus CBS 931.73.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Basidiobolomycetes; Basidiobolales; Basidiobolaceae;
OC Basidiobolus.
OX NCBI_TaxID=1314790 {ECO:0000313|EMBL:ORX94275.1, ECO:0000313|Proteomes:UP000193498};
RN [1] {ECO:0000313|EMBL:ORX94275.1, ECO:0000313|Proteomes:UP000193498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 931.73 {ECO:0000313|EMBL:ORX94275.1,
RC ECO:0000313|Proteomes:UP000193498};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TOG/XMAP215 family.
CC {ECO:0000256|ARBA:ARBA00025722}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX94275.1}.
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DR EMBL; MCFE01000209; ORX94275.1; -; Genomic_DNA.
DR STRING; 1314790.A0A1Y1Y8S1; -.
DR InParanoid; A0A1Y1Y8S1; -.
DR OrthoDB; 5477703at2759; -.
DR Proteomes; UP000193498; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0099080; C:supramolecular complex; IEA:UniProt.
DR GO; GO:0061863; F:microtubule plus end polymerase; IEA:InterPro.
DR GO; GO:0051010; F:microtubule plus-end binding; IEA:InterPro.
DR GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IEA:InterPro.
DR GO; GO:0046785; P:microtubule polymerization; IEA:InterPro.
DR GO; GO:0007051; P:spindle organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 5.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR045110; XMAP215.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR12609:SF0; CYTOSKELETON-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR12609; MICROTUBULE ASSOCIATED PROTEIN XMAP215; 1.
DR Pfam; PF21040; CEP104-like_TOG; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 4.
DR SMART; SM01349; TOG; 5.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000193498};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..224
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 266..498
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 435..473
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 612..844
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 875..1110
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 1277..1507
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 235..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1106..1226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1494..1627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1945..2022
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2089..2112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2151..2186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..527
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1516..1544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1945..1969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1983..2008
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2154..2168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2186 AA; 240588 MW; B8CC7A104590E33D CRC64;
MADNDFSSLP LEEKIIHKVW KARLEAYEEL TKLYKTTDQE AEFDKYSEHF KKFVTDSNVA
AQEAGLTAVT AYVENAPTPT RTRESVVPGV VEKCFGSTRA GTKAKAVELL LLYIEVDVPD
PVVESVMTGL DSKVPKIVAA TVFALKEIVR LYGAKVVNVK PILKVLTKIF GHADKNVRAE
GTQLVIELYK WLGPALNPAL QDLKPVQIKE LNEAFEKLPA EKPVAERLLR SHQAIQAPAN
ESAADNDDAT DGGSMPTEDS EIDPYDLADP VDALKKLSPS FYTDLASTKW KERKEALEGL
LAIVKTPKLV DDNYSELTAA LAKRIGDANV MVGTASANCI EAIALGLRKN FGPHKSTVVP
PVLEKLKEKK QTVVDALRAC LDAVFSTVEL SDLVEEVTAA SGHKNPQVKA ETHRWLTRCL
KTIKVAPGKG EVKWISELFL KGLDDGDTNV RDAAAEGLGT LMKAVGEKVL APFIEKLDKI
KEAKVREYFE KAEVKVVQAV PKKPVVAAKK PAPLPRKPAP APPPSEAIKP MNDGGLDENL
LASTPAAPKA KPPARLAARL AKKPVSAEEP AAPAAAKAPP KPAAPKPAAT AKAGPVKVAA
VKLKPDEPIR FKYSNDDFEA HVPDVIPDAI LKELLSSNWK SRLAAMESLH THLEENLEST
EPELIVRQLV KKPGFKEVNF QVSTKMYGIF QLLCEKAPSF TKGCAVLTVA GMAEKLGDIK
LKKPAGECFS AYGEKYSLQF VLHHSYESWK KAKSPKVLAD SLVWVKETLM EFGIAGLDVR
ELIEFLKTAL GSSNAAVRNN SVSVLGCLHM YVGPDIRSFV QELSSTQLST IDAEFAKVAG
QTPPEPVKGL ALLETVTAAP SGKGGAAKSV DLLDDLFPRV DISSQINSKL LKLLEDGNWK
VRKEGLDEVQ KILEAANKRI KPNVGDLPGA LKGRLGDSNK NLVILTLEIL STMAVAMSQP
FEKPCRIVLP SVLGCLSDNK AHVRAAAINA LDKFRESCTL TPMIPAIGTV LVPDSPVLRK
DLLSWLSDKL VALESEGDEL PDLSSLVRPI FQCLQDRSAD VRKHAQSVLA FLIKNVGYSS
VRDQCSTALK GSSLQTVLAI IDGMKPAGAA SSKPTNGPGK ISPTDKKAEF KRPSSVASNS
SDSKRSVSGS SDMKKGATSV SSIIEKKRAT IIPPPSPNKN AKGEEPPTAV PNLKPRAILN
KRKSMMPPPT QLKAPSPSME GEPPILTSDA RAKNARADKD RNQNKWAFDA VRQDLVDLLA
DQMRPHFNPD VHKLLFSMEH NRDRDMLSGL TALDDCIANR HYAQDRFGLD FEDLKERYIA
NSDTLLKYTT LRFYDTNTSL SLKTLELLEH LISLLEEDGY HLSEYEASAF LPQLINKLGE
PKEVLRNQLR SILKQVYHLY SPNKVAMFIL EHGLKSKNAR TRAECLDELS SLIKGNGINV
IPIKSFPVIA SHIGDRDAQV RNNALSAIVQ AYLQIGDTIY KYTGKLSDKE KTMLDEKLKR
SKPPASGLPK PHDRPSTPQS KLSIPRAGTS LGHSESQFEK SPARLQRPMS TLPKPSPALP
RPSSSLAKPS LFPRPSSALS NSSSLSISPS SSPKPHRPMS FLPRPGGLGK EEMTPERRTP
DLPQTPAFHE YQSPQAVSRA PLFENTFTPT TAQIGPIQPK VDRHRVDMFA SKITTADASE
IVLLMKSIGD ILNDDYTLLL PNLNNIVSAM TLKIHILFEE PELDSQPWCR QIKHMLLVFT
KMFMKKDVAC DLRVDVLENT IEQVLKLLLQ EDLQKVEQTS NSPSMDKTLN TLLTKIIDHT
DQNALYQALF ALYERTLSDF LGRPKDFDTP ITESEEYKLF DVVQKCIWKS SRSLKAHIEQ
HTIDLDRLFL MIHEFLSRVN PTEWRKKAHA KGLTTQDNPM KTAKAVLFHA AGALQADVLN
HVTLIPSPES SLVVVYLRSY LDKAKGSSSV SGSLNTETNG VSGNPSMTPT FAAPGALRPN
ADNLSEDEGH SRAVESQSRH DSDEWDENGV KGTNPNQEMS PMDQMNHRLD RIFELIYDRK
HTKQGVNELH ELLQAQPEAQ EEFEKRLSKA SKYFQSFIRR SLSNLSGEFQ SPDMRSPMAS
NIQPQSPRSS SRISYRESVA SFEELLGQHA KTEPDNSQHV RIQEIQRMFG FRRGSLESHS
ETDSPSAEEK LTSPRTQLAN PFVGDI
//
