ID A0A1Y1YC60_9FUNG Unreviewed; 954 AA.
AC A0A1Y1YC60;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE SubName: Full=Rad4-domain-containing protein {ECO:0000313|EMBL:ORX95525.1};
GN ORFNames=K493DRAFT_260436 {ECO:0000313|EMBL:ORX95525.1};
OS Basidiobolus meristosporus CBS 931.73.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Basidiobolomycetes; Basidiobolales; Basidiobolaceae;
OC Basidiobolus.
OX NCBI_TaxID=1314790 {ECO:0000313|EMBL:ORX95525.1, ECO:0000313|Proteomes:UP000193498};
RN [1] {ECO:0000313|EMBL:ORX95525.1, ECO:0000313|Proteomes:UP000193498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 931.73 {ECO:0000313|EMBL:ORX95525.1,
RC ECO:0000313|Proteomes:UP000193498};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX95525.1}.
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DR EMBL; MCFE01000173; ORX95525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1YC60; -.
DR STRING; 1314790.A0A1Y1YC60; -.
DR InParanoid; A0A1Y1YC60; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000193498; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR018026; DNA_repair_Rad4-like.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR NCBIfam; TIGR00605; rad4; 1.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000193498}.
FT DOMAIN 673..724
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 726..791
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 798..872
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..290
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 954 AA; 106864 MW; 4F35F512CC09A84A CRC64;
MPSKGQSSSV TPKKRRTPTK TLPATDDDVS DGFIDIQNEA SPCRHKLRIE MPPSPPPMPA
MLESDPEETF DLELDLNPQL ESEPETAEKH DAIVRKRSNV HPVNREEPSA KKKQKNTQSR
FSVDIDRVNS HAEAAEKQVD DTQGLDLQSK SIHSNARNEL TSSHKSIDQS NEEVGKPAIA
QQAESLDATD EPQILKIEKS PAIITSKFFE DSPGGPMPRK ILGKSVIKSE NPSLDIAERA
DDGTAHRLTA SAEQVPAAKS TDFPTIEEEK PERHESDEES EEEEDWEEVA VPGNGSEKSS
TVAESQVSAD EPYEETKFKT LTITLDTPKV KPRAKSSGLS KMERLIRLET HKAHLLCLLA
NGIYRNNICN NSELRALTLS TLPKKIYASL SLETRKDTAT VKNSRFLIAI EKLASWWYAY
FEVIGSECQT TDQEEVVESE EVADSMNLQH LTNSLNYPRG SAEVSTQLFV ALCRAVGLTA
RLVISLQPAP LKAPTSSSKN GNSDVSSSAS SPKTTKKSAR RRGKQRSGVA DVESGVMKTI
KEEVTASKSK YFGQKREAEG EPPLFWAEIL SPYNNKWVSV DCVRGLVSKV AEMEPSADNP
YSLAYVVAYE ADGCIKDVTR RYTRQWGAKT KKLRVPVAKD GYDWWGETLS FYARRYKSQA
DELEDAELLS CEVSEAMPTS IAAFNNHPLY VLERHLKKFE VLHPQGPVIG HIRGEPIYPR
SCVKETHTTE TWLKEGRTVK PGEEPVKYVK ARVVTINKQR MHNMMAMDSG EAVDPQSALY
GIWQTEEYRP PPVVDGKIPK NKFGNIDLYK DSMLPEGAVH LPFKGIARIA KKLEVDYAEA
VVGFEFHCRR CIPVVKGIVV PVESKEIIME AYEEFERNRQ EKEFTKLEMA ALAKWRKLIT
GLRIHHRLKE EYGNDPEEER FEEEMDDVEL SKTPNDVPSP EPKPEIDTGA GFFL
//
