ID A0A1Y1YCD3_9FUNG Unreviewed; 622 AA.
AC A0A1Y1YCD3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=phosphoserine phosphatase {ECO:0000256|ARBA:ARBA00012640};
DE EC=3.1.3.3 {ECO:0000256|ARBA:ARBA00012640};
DE AltName: Full=O-phosphoserine phosphohydrolase {ECO:0000256|ARBA:ARBA00031693};
GN ORFNames=K493DRAFT_219585 {ECO:0000313|EMBL:ORX95274.1};
OS Basidiobolus meristosporus CBS 931.73.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Basidiobolomycetes; Basidiobolales; Basidiobolaceae;
OC Basidiobolus.
OX NCBI_TaxID=1314790 {ECO:0000313|EMBL:ORX95274.1, ECO:0000313|Proteomes:UP000193498};
RN [1] {ECO:0000313|EMBL:ORX95274.1, ECO:0000313|Proteomes:UP000193498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 931.73 {ECO:0000313|EMBL:ORX95274.1,
RC ECO:0000313|Proteomes:UP000193498};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Amino-acid biosynthesis; L-serine biosynthesis; L-serine from
CC 3-phospho-D-glycerate: step 3/3. {ECO:0000256|ARBA:ARBA00005135}.
CC -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. SerB family.
CC {ECO:0000256|ARBA:ARBA00009184}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX95274.1}.
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DR EMBL; MCFE01000181; ORX95274.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1YCD3; -.
DR STRING; 1314790.A0A1Y1YCD3; -.
DR InParanoid; A0A1Y1YCD3; -.
DR OrthoDB; 789at2759; -.
DR UniPathway; UPA00135; UER00198.
DR Proteomes; UP000193498; Unassembled WGS sequence.
DR GO; GO:0036424; F:L-phosphoserine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd07500; HAD_PSP; 1.
DR CDD; cd14447; SPX; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR004469; PSP.
DR InterPro; IPR004331; SPX_dom.
DR NCBIfam; TIGR01488; HAD-SF-IB; 1.
DR NCBIfam; TIGR00338; serB; 1.
DR PANTHER; PTHR43344; PHOSPHOSERINE PHOSPHATASE; 1.
DR PANTHER; PTHR43344:SF2; PHOSPHOSERINE PHOSPHATASE; 1.
DR Pfam; PF13740; ACT_6; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR SFLD; SFLDG01137; C1.6.1:_Phosphoserine_Phosphat; 1.
DR SFLD; SFLDF00029; phosphoserine_phosphatase; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023299};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000193498};
KW Serine biosynthesis {ECO:0000256|ARBA:ARBA00023299}.
FT DOMAIN 1..159
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT ACT_SITE 409
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR604469-1"
FT ACT_SITE 411
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR604469-1"
SQ SEQUENCE 622 AA; 69600 MW; 7166942B783240A2 CRC64;
MKFGNFITAR KVNYPEAWVP YTIDYVALKS FIKQNIAPDS LALSKLTPEQ LQWTVDSAQE
NSYANIITSR LGKLQILVGD FLAMLDKEVH LLNEFYVEET ERIVSYHRQS EEDTLTSKEI
LQCIIKLESF VLLNYTAITK ILKKHDRHSG LKISDSYLLR ISNMSFVRSE NLLTLKRVLL
RELGESPLPP SCTSPELILS KKISPAEKKN WFPTAALLPH QKVLVSLTGP HGTDIIGCIL
QCASKHNCDI EDFMFSRLYH TATFGVLITL TNDNVAIFQD LAEAARRWDG TLSFEIQENH
GPLPKSIEEA PYQDRVKYAA TILNQNGLSA KFLYEWTHLL LKHKISVEKM ARLNEGHVSC
ADYKLSVPKT VDYDSLRVQL FQLSLSHGTD VAMQPYDVFR RNKRLVVFDM DSTLIQQEVI
DEIAKHAGVV DQVAAITEAA MNGEIDFKES LRRRVGLLKG TSVSVLDTVK ESLTFTEGAR
VLCKALKKIG LKLAVISGGF MPLASYVKNE LGLDYAFANQ LKVSSDGLTL TGETVGPIVD
GQRKAELLEV IAQAESVTLD QVIAVGDGAN DLWMLAAAGL GIAFNAKPKV QERASTRINQ
KSLKYVLHLL GYTDEECRQL YE
//
