ID A0A1Y1Z0C9_9FUNG Unreviewed; 2121 AA.
AC A0A1Y1Z0C9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Dedicator of cytokinesis protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=K493DRAFT_297523 {ECO:0000313|EMBL:ORY03265.1};
OS Basidiobolus meristosporus CBS 931.73.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Basidiobolomycetes; Basidiobolales; Basidiobolaceae;
OC Basidiobolus.
OX NCBI_TaxID=1314790 {ECO:0000313|EMBL:ORY03265.1, ECO:0000313|Proteomes:UP000193498};
RN [1] {ECO:0000313|EMBL:ORY03265.1, ECO:0000313|Proteomes:UP000193498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 931.73 {ECO:0000313|EMBL:ORY03265.1,
RC ECO:0000313|Proteomes:UP000193498};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY03265.1}.
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DR EMBL; MCFE01000048; ORY03265.1; -; Genomic_DNA.
DR STRING; 1314790.A0A1Y1Z0C9; -.
DR InParanoid; A0A1Y1Z0C9; -.
DR OrthoDB; 8258at2759; -.
DR Proteomes; UP000193498; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd11684; DHR2_DOCK; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046770; DOCKER_Lobe_B.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20422; DHR-2_Lobe_B; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000193498}.
FT DOMAIN 575..775
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1504..1952
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 310..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 839..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1739..1776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1965..2037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1749..1775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1967..2037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2121 AA; 237424 MW; A0B2CF8AE439151A CRC64;
MPMWQPLARV ANGIAIFPFL SVTPSVVNEA PEDNGDSQLF LLDSASPDAS YFVDLEVGDI
VYAYEQLDGW YKGYVISSFP PNSQPRCGIF PANHVHIRSY QASPTATASS KLQPDTTRHL
ISEKQRLSPE IAKAPSLMRS NSELVARSSF DSTSTTSSNR IRPLSLQEKN LDSIHPSPPT
IPQLKPYRTA SGYLEPLVDI ISDVLKEWCS YLPTYLRKCE YELFNTVKGY MSTLFKGRRQ
LLSQTLSLED LNKLRSELIH TILSGNKLQG LDSIVLHKEK GLPIDEKHSP LTALYKSHVE
LSGDAGGQLE SPLVTSPHHS PLGVNSTPVR KKTPKAAVDS ISSLYHLFFD LKAFVASICS
TGEYAELHFS LFNKTSSKFI SEEFLIVLTS QGMPSDPNRI GRLRTLFSDL SQKDVSDQIY
LVCRIVRIGR TLLLEKSKDG IELSSSSSAD VSSRINSISN KPGSEVINYR RPFGCAVFSV
SDVLQASSQA DAMRESVIKI YTPLNDTTFS TLHENIINQT GEYEQSSRAE SICVSFRVFQ
GQAQALIREH PTLLLDIPIT PRLGFPDVVL PGDNRNAMHL TLCSGDFQQG RRATAKNIQV
KVEVRSNEGN GAALGGAICR GSGEANVTQY ESTVIYHSNN PRWDEAIKIE VTPDIFKSSH
IFFTFRHCSS KEQSGSTISL GSKEKSTDSS IFAFAFLPLS LENHHTIVSD DTHTLTLYKY
DPKIVSSTTY LKCCTNTPKP NKLMSFDSLD LVKSYTSSSG ITPLKDTFVV KTFLCSTKLT
HSESLVNLLH WKEALLTRHD MRSILKNFTF IGELEIVKFL QDIFDVLFDL LGAPPSSFQH
GDTPVRQNSH QRQPSVSGAG PTLDDLVFAA LVFVLNIVSD RRFTNFRPVL DVYIENHFSS
SRVSKHLISS MRKLLSDPTD STQAMGLRSS IKAWEYLFKL IVKSWGIHRA EEKGKNLSNA
GAPMSSPLDD SVGSQSEFKA SLWGLFGDIN GLMSLSTPLS ILGTQTIALQ HYHTIFQDLV
TRFPINELAE VAVEFVDSVA NFRKGNLAHH RLRLVYQLLH GVLFDCPESR HILVKATVGW
VEEYLEQPMT DYADLEQWRE MLRLSYLVVA EMLEKIHSTF YKDQPDGYPS SNQAELEDPD
VEVMLNILPL LLEVYHRLRQ VSMPNTFDQH GAATSKHNSG LSGPLSPLSS SPELLPVEIH
DRSSNILGET ASMILTLISL TSSNQLERFF RACLAGPDSD DGLQVVVLLL DILHSTLSEN
AFPRHWLNLS VLSLKMTFKA LIPLSNVLRQ NLDTSERISE PLVNIWVKFY TVLVFILASK
RLKIEVLKPQ LQSATIYLLQ DVRAQGPNLL VVMWHCLESF KPRIDRDQYR HIILTLLGPI
LDLNLTLHDG LRKCALDILY AIMLSEYEMK ESFKDMEVEC FDRLEHLVMT ETKGDLGTYN
LFIQGLVSKI EKEKSDVSLN LALIKLVDSV NKFLELLLNV RDLPNEDQYE DERIMGTMKL
LRFIKIMNQD EIYIKYVHQL VDMHLRSQNF IEAGITLKLH VDLLDWSSKN HLEAMSSLAL
PSQSTFERKE LLLSKILNYF NEGQAWEHGI EVCKELAHQY EHVSFDYDRL ASILRTQAQL
YENILHKERY YSEYFRVGFY GKGFPTSVRN KQYIYRGLAW EKISAFCDKI QNKHPSAQLL
NSNGTPSEAI LNSNRQYLQI TAVTPEPNMQ LSLLQQPDLV PGPVREYYEA NEVNTFSFSR
PVKKSPTGEM ASPRNSTLLG SKLTASGSSK HLVPPGGTDQ VNEFLMLWTE KTILVTESKF
PSLLRRAEVI STTTKEQSPV ENAVAAMESK TKELSHLEKK YRVYVGTDTS KVNSNPLAMA
LNGAIDAAVN GGVSMYKRAF LTAEFIKQNP DKEDLVERLR QLIDEQTLVI QSCLEIHNRI
APSEMRPLHE NLDMLFRKNF ANELVRISAK KPTIALYQPP VPFNTPSPQV TSHHTPLASA
SLSNPHRSTG STQSLQLNKR DSQLSDSGGF DPALTLSSPA SQSADNTSPS TRSSNPFTFA
LKRLSGGSST TCSSMDGTDI DYQSLTAVGS PSLATASLSN PADLPNLGKK NRWSLKKYRM
LLERHLATNN SPTATTEGTH S
//
