ID A0A1Y1Z6E8_9PLEO Unreviewed; 323 AA.
AC A0A1Y1Z6E8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=3-hydroxyisobutyrate dehydrogenase-like protein {ECO:0000313|EMBL:ORY05694.1};
GN ORFNames=BCR34DRAFT_490715 {ECO:0000313|EMBL:ORY05694.1};
OS Clohesyomyces aquaticus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Lindgomycetaceae; Clohesyomyces.
OX NCBI_TaxID=1231657 {ECO:0000313|EMBL:ORY05694.1, ECO:0000313|Proteomes:UP000193144};
RN [1] {ECO:0000313|EMBL:ORY05694.1, ECO:0000313|Proteomes:UP000193144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115471 {ECO:0000313|EMBL:ORY05694.1,
RC ECO:0000313|Proteomes:UP000193144};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY05694.1}.
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DR EMBL; MCFA01000123; ORY05694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1Z6E8; -.
DR STRING; 1231657.A0A1Y1Z6E8; -.
DR OrthoDB; 203032at2759; -.
DR Proteomes; UP000193144; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22981; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR22981:SF81; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000193144}.
FT DOMAIN 1..140
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 172..296
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 178
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 323 AA; 34824 MW; D45B3EC181693179 CRC64;
MGYAMASNIR KKMPTDSILY INDIDPSACE RFTSEYSSLG RIEIVSTARE AAQNSKVVIS
IVPAAVDVKN VYLNEKDGVI AGTPDTARIL CECSTIDVKS TREVGEALMR KGMGTYVDTP
VSGGVPAAQR GDLSMLIGHS PPDPANPNTL LLERVLGMLG SPQKFFYLNS LGLGLTAKIS
NNYLSGTILL ATAEALAIGI KQGLDPKMLY DVIKASTGQS WMCDHVMPVP NVVPHVPSSS
GYKPGFKTQM MIKDLGLGVE AGKQVGIRPL MAEAAMETWE RASKDERCFD RDGSSVYLHI
GGPLPDGYED RGKKKEDGTW EFA
//
