ID   A0A1Y1ZE35_9PLEO        Unreviewed;       710 AA.
AC   A0A1Y1ZE35;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
DE   Flags: Fragment;
GN   ORFNames=BCR34DRAFT_14589 {ECO:0000313|EMBL:ORY08227.1};
OS   Clohesyomyces aquaticus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Lindgomycetaceae; Clohesyomyces.
OX   NCBI_TaxID=1231657 {ECO:0000313|EMBL:ORY08227.1, ECO:0000313|Proteomes:UP000193144};
RN   [1] {ECO:0000313|EMBL:ORY08227.1, ECO:0000313|Proteomes:UP000193144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 115471 {ECO:0000313|EMBL:ORY08227.1,
RC   ECO:0000313|Proteomes:UP000193144};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC   -!- SIMILARITY: Belongs to the putative lipase ROG1 family.
CC       {ECO:0000256|ARBA:ARBA00007920}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY08227.1}.
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DR   EMBL; MCFA01000103; ORY08227.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1ZE35; -.
DR   STRING; 1231657.A0A1Y1ZE35; -.
DR   OrthoDB; 1785483at2759; -.
DR   Proteomes; UP000193144; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR007751; DUF676_lipase-like.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48182; PROTEIN SERAC1; 1.
DR   PANTHER; PTHR48182:SF2; PROTEIN SERAC1; 1.
DR   Pfam; PF05057; DUF676; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193144};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          381..539
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         710
FT                   /evidence="ECO:0000313|EMBL:ORY08227.1"
SQ   SEQUENCE   710 AA;  80718 MW;  DF3D04B7E4BDEF86 CRC64;
     MPSKFNLFKR KKKDDPEQAV GSREVASAQG SHNEATDDEA EEVCGLFDFD DDPPSEALFD
     IVAVHGLGGH WKHTWTGDSG SLWLRDFLPT EFKSLGFKVR IRSYGYNSNT AFSKAVTDLS
     NEAEMLLDRI RGERGTEEEK SRPILFVAHS LGGILVKKAM IAAHERSEIY GDILKKIHGV
     AFFGTPHRGS DLAWWADFPA TLVKALQLGR GTNKAYVEAL KRNSKEFSDI SRQWVERAKG
     LRIRTYYETE RLLGFLVVDE DSARLNLPNE IPTGIAGANH KTICKFDKEN GQKYRQIWNG
     IKEIAIDISE ARKISKASKE TTNDTNIMFE VNEQHKQFLR LLCSSDYEAD RRRNPEREQG
     TCEWIANDDH YQTWFSEKRS NILWISGDPG CGKSVAASYL VDHIRSSAEG YTPVFFFFKD
     DSERQSSANM ALCAILHQIL SIDQNKPLLE LAMPVYTSHG SALLERFDSL WSILIKVVSD
     PRCGELVVVL DALDECAKKC REQFMTNMVA LCIRAKEHDN ENPTRVKFLL TSRPYAEVER
     ALKNFQAIRL KTEESVDKIE QDVKRVIDAR IQRFADRMEV SEDTRLKSLK KNLHSKADRT
     FLWVSLTLDM LDNSEDCTYA ELADIVNASN PGIDALYEKI LQKAKDPKKA QRMLHLVVGA
     VEPLSVEEIN VAWAIEVGKE CDLEHRKFPS PERGIREVCG LFVRIINKRV
//