ID   A0A1Y1ZFV1_9PLEO        Unreviewed;       967 AA.
AC   A0A1Y1ZFV1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Mismatch repair protein 5 {ECO:0000313|EMBL:ORY09079.1};
GN   ORFNames=BCR34DRAFT_603100 {ECO:0000313|EMBL:ORY09079.1};
OS   Clohesyomyces aquaticus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Lindgomycetaceae; Clohesyomyces.
OX   NCBI_TaxID=1231657 {ECO:0000313|EMBL:ORY09079.1, ECO:0000313|Proteomes:UP000193144};
RN   [1] {ECO:0000313|EMBL:ORY09079.1, ECO:0000313|Proteomes:UP000193144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 115471 {ECO:0000313|EMBL:ORY09079.1,
RC   ECO:0000313|Proteomes:UP000193144};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY09079.1}.
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DR   EMBL; MCFA01000091; ORY09079.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y1ZFV1; -.
DR   STRING; 1231657.A0A1Y1ZFV1; -.
DR   OrthoDB; 9867at2759; -.
DR   Proteomes; UP000193144; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   CDD; cd03281; ABC_MSH5_euk; 1.
DR   Gene3D; 1.10.1420.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193144}.
FT   DOMAIN          778..794
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|PROSITE:PS00486"
FT   REGION          1..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          657..690
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        671..690
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   967 AA;  106518 MW;  72FC0B57ABADF8C3 CRC64;
     MAARFAFRKK YGQRSSSSAR SDRSRSSRRS AADPVRAPAS RSAQSRAQSS SSVPLPQSQQ
     CEENDNEDDS LDEIVMAVDL RDRGTVGCCY YVAKEEKLYF MEDMKLGGAD IVNSLKAFIQ
     PTVVLLSTKI DDEVIEKLDP ENKSRGSGDG SIDQFRLPFL LEVRPHFEFA YEAAKSKLAQ
     LRIGEDDGPQ VTFVVPGDVV AANWAYDNGD AAGRQDQLLR LSGWVDMESQ LTVGCAGALL
     SYLQRRRAAA YLPGDENAHL MFRISVLEMF TMKDTMFVNM DTLHSLQVLE SESHPHSHNQ
     GPTKANSCSK EGLSVYGLFH HLARTPQGRI LLKQYFLRPS LNLDVIHERH ETISIFLRPE
     NADPFDSIIS NLQKVKNMRV IMINLRKGVG GGIAKGGGVS KSVWTGIRQF AFHALQIKDA
     IQEVVGAEHI GMRNKVLETF ESYHLAQVGR QINEIVDFEK SAEESRTVIL PGIDEELDQM
     KATFAGLDAL LSQVAHKLSE RIPAGLQESL NVIYFPQIGF LTTVPVDPDT GSGVYVGGLE
     NPWEQMFSTE EQVYFKNIEM REMDDHFGDL YGIISDREIE ISHELAQYVL EYENLLTAAS
     DICGELDSLL ALAQGAKQYK LCRPRVIKDN VLQIKGGRHV LQELTVASFV PNDTTLVGGA
     GDEPAQDASN DGGDRFTSQD QRQTNTSSRS AYRLEGPSML IMTGPNYSGK SVYLKQVALI
     VFMAHVGSFV PAQSARIGLT DKILSRVTTR ETVSRSQSAF MIDLQQISLA LSLATRRSLL
     IIDEFGKGTD TSDGAGLACA VMEYLMNLGD ERPKVVGATH FHEIFETGLL KPRPSLAFGH
     MEVRVDTEAS EVEDQITYLY NFNEGRSTSS FGTCCAAMNG IPPEIVQRAE ELILLSAKGE
     DLVAACSVMP DSDAAELEEA EQIARDFLEA AVDTDPRTVL GSILAVSTTT GSRAWSPTKA
     QTFALFC
//