ID A0A1Y2A4B1_9PLEO Unreviewed; 626 AA.
AC A0A1Y2A4B1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Alpha/Beta hydrolase protein {ECO:0000313|EMBL:ORY17353.1};
GN ORFNames=BCR34DRAFT_555920 {ECO:0000313|EMBL:ORY17353.1};
OS Clohesyomyces aquaticus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Lindgomycetaceae; Clohesyomyces.
OX NCBI_TaxID=1231657 {ECO:0000313|EMBL:ORY17353.1, ECO:0000313|Proteomes:UP000193144};
RN [1] {ECO:0000313|EMBL:ORY17353.1, ECO:0000313|Proteomes:UP000193144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115471 {ECO:0000313|EMBL:ORY17353.1,
RC ECO:0000313|Proteomes:UP000193144};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY17353.1}.
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DR EMBL; MCFA01000013; ORY17353.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2A4B1; -.
DR STRING; 1231657.A0A1Y2A4B1; -.
DR OrthoDB; 5474043at2759; -.
DR Proteomes; UP000193144; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR PANTHER; PTHR11005:SF103; STEROL ESTERASE TGL1; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ORY17353.1};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193144};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 136..431
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 453..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 70153 MW; 1E0704C152FAA820 CRC64;
MALHIPFLSR LHLRQYFALF LSIFLIALES LISIITLALP TPIIAFCYRI TRRLFNYLSS
PSSKRSRQKK KGVWSSIATA SDFTELCELY GYYAEEHIVQ TGDGYLLGLH RLGWRRGEED
VRVNAGDKKG GVRKKVVYLH HGLMMNSEVW VCLTERERCL PFELVERGYD VWLGNNRGNK
YSKKSVHTAP TSTAFWDFSM DQFAFHDIPD SIDYILSTTH QPSLSYIGFS QGTAQAFATL
SIHPNLNDKV DVFIALAPAM SPKGLTSPIV DSFVKASPDI LFLAFGRRAI LGSATMWEAI
LYPPIFVRLI DASLKFLFGW TAKNITPHQK LASYPHLFSF TSTKSVVHWF QIIRNKTFQM
YDDEAPNPVI SNRGKYYKVA KFPTKNIKTP IVLVYGGSDS LVDIEVMLKE LPRHTIAKEI
PHYEHLDFLW ASSVDELVFP HVFEALDEYA GSDGAGFEPR KEKRLRSPGR YRGLLPESGA
LPGPEGDDAG DESSSSPAVL RAKKVSQNTR RISFSDRQQE HNPQDPHTPS PHASKIPHSA
STYASAVSDR SHSLNQPTTK FSPPASRIPT HTFLNQNQNQ SNPNSKSPAV SVNASQMTAQ
SSTSRPEGWW SSDEVAGTGH TANREN
//
