ID A0A1Y2AQC3_9TREE Unreviewed; 1224 AA.
AC A0A1Y2AQC3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Sodium/calcium exchanger protein-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR39DRAFT_472108 {ECO:0000313|EMBL:ORY24674.1};
OS Naematelia encephala.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Naemateliaceae; Naematelia.
OX NCBI_TaxID=71784 {ECO:0000313|EMBL:ORY24674.1, ECO:0000313|Proteomes:UP000193986};
RN [1] {ECO:0000313|EMBL:ORY24674.1, ECO:0000313|Proteomes:UP000193986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=68-887.2 {ECO:0000313|EMBL:ORY24674.1,
RC ECO:0000313|Proteomes:UP000193986};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000256|ARBA:ARBA00008170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY24674.1}.
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DR EMBL; MCFC01000065; ORY24674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2AQC3; -.
DR STRING; 71784.A0A1Y2AQC3; -.
DR InParanoid; A0A1Y2AQC3; -.
DR OrthoDB; 8346at2759; -.
DR Proteomes; UP000193986; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProt.
DR GO; GO:0015369; F:calcium:proton antiporter activity; IEA:UniProt.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 2.
DR InterPro; IPR004713; CaH_exchang.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR InterPro; IPR005185; YccF.
DR PANTHER; PTHR31503:SF10; CATION_H+ EXCHANGER PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR31503; VACUOLAR CALCIUM ION TRANSPORTER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
DR Pfam; PF03733; YccF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193986};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..635
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 690..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 724..746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 758..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 832..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1035..1058
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1070..1091
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1103..1123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1135..1156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1168..1185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 315..368
FT /note="Inner membrane component"
FT /evidence="ECO:0000259|Pfam:PF03733"
FT DOMAIN 660..778
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 1032..1183
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 1..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 981..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..256
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 981..1005
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1224 AA; 132315 MW; 1ECFCC4D1C8544DE CRC64;
MSNSGEATPR GTQRGIPHTA YGSAFGSPNN QHGQMSSDDS ALRPARAPRY NTSQGFPPGH
NNHAWQGTGS MSRSGSRARP PLHTRNSGGQ IGLVSSALAK NGGGDEDDEA EIEDRGQALI
RKRQRERKQR RRAQEKERER RLESMTPDAS APPTGQPDEG FAAQQARSLR SASRSRGPSS
SRRTPSEAYA GSISASEARD GSQSPRDELR PSSIYSTGDD EDDTPTADRQ SLLEDVVQEV
LDEAAEESGE EEASGEGDEG VTLKDRQDAI NIEHPFGLPI WKPALYRKSR SVTRNAESAL
HSIPSAAAER HLLPGNILWV ILFGWWLALV CLLAAIFVSA AEVLGGGRGG YGKTLRGLAW
YIGWPFGKYV EGEGAPENEA EADAQHDEES ANGSPKYRRR VASDGASSGV TVRGTRPQPE
TEHPSPTTRN ERTDRRETTV SFAPTVKGAT TDSLRAFSDG SVDERAPLLP KQGFRRPRNK
RAKILGRIIY WPAFLLLVAP LMLCVCVLCW GMVITIPMAK LTWALLELLT FRPLEINFRS
APKIPVPTPG SPSSGEDSGD TTAVSDSSPS GFTLKRARLT AGQVAPTSGP KSTVLLCTYR
AIGLQYYKYT VGGVNIMFIN LVPLVFFTII DGLLIRPRVE HGIEHGHMPS HFVGFITSPA
LIFTLALASV IPLSYFIGMA VASISAQSSI GMGAVINATF GSIIEIILYA IALMQGKGRL
VEGSIVGSIL AGVLLMPGAS MCSGALKRKE QKFNAKSAGV TSTMLIMAII GTLTPTLFYQ
TYGTFELHCE GCPEPSGNTT IAADVAWQCN HCYYEHPDPA YDPFYQDQVK TLMYACAAIL
LFSYLIGLWF SLRTHASQIW QNPQQLMKVD EIAGIHPSQR QGVYNRVTPQ AVMQHILPLH
RAPTSQGGGS LRVPPVIDEE PRTASNSYDL PAGYTPFLDS VDRDIKNPQI TPIRLPHTLT
TEDFTRAVAV ATVSALRHQG SIIGSHSGSA QRPRPMNSET HGGQGHSTEG AGAEEEGEAG
GHEAPSWNRG VSTGVLLACT LLYAIIAEIL VDVVDVVMQG SGLDEKFLGL TLFALVPNTT
EFMNAVSFAM NGNIALSMEI GSAYALQVCL LQIPAMVAFS AFYDPGKMGE VVDTFTLIFP
RWDVIAIILS IFLLTYTYIE ARSNYHRGSI LVLAYVVLVL GFYYAPPRSQ GDPSTDSRIE
PALVAQGVEA IGMGFQVALS KLWA
//
