ID   A0A1Y2BDX4_9TREE        Unreviewed;       636 AA.
AC   A0A1Y2BDX4;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Rho GTPase activation protein {ECO:0000313|EMBL:ORY33022.1};
GN   ORFNames=BCR39DRAFT_564013 {ECO:0000313|EMBL:ORY33022.1};
OS   Naematelia encephala.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Naemateliaceae; Naematelia.
OX   NCBI_TaxID=71784 {ECO:0000313|EMBL:ORY33022.1, ECO:0000313|Proteomes:UP000193986};
RN   [1] {ECO:0000313|EMBL:ORY33022.1, ECO:0000313|Proteomes:UP000193986}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=68-887.2 {ECO:0000313|EMBL:ORY33022.1,
RC   ECO:0000313|Proteomes:UP000193986};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY33022.1}.
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DR   EMBL; MCFC01000007; ORY33022.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2BDX4; -.
DR   STRING; 71784.A0A1Y2BDX4; -.
DR   InParanoid; A0A1Y2BDX4; -.
DR   OrthoDB; 5482027at2759; -.
DR   Proteomes; UP000193986; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR23176:SF134; ACTIVATING PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00055; FCH; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193986}.
FT   DOMAIN          23..328
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          425..617
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          188..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..413
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  69552 MW;  7717461C7F866093 CRC64;
     MGSAGSLKVG GNGLEVKEDV VPVGFDEGLL RGLCEMDCAL PLLADRIKQS IASCKQVAVF
     FRSRAEIEEK YARSLTELCR TTGDVYSRAD CKAGTFVAAY QSSLKLQNSL AENRIRFSQR
     LNEMSDELLG LAREGEKLRK MHKENGARYQ GILQESEMVM DKAKARFDAT AEELERVLVA
     KEGESIKESG MRSGGAGSSS GGNKGRGIGK AMTKGGLLFK GKGAASMQRQ EDDVRARMAQ
     ASETFRKAVL ESQALRQEYF NFQLPKILRL LKECADELDM GTQYHLARFA FLYESTVVGE
     GTLLNPMGAP DDGPGLKAIF EGIDNRTDFK SYMQNYAVAR GTPRGPRREG PYEEGFLPPL
     PPHVQKGESN PNQVSQQSNG ISNTNGHPSG ANNNLPTPLP VSQAPSSEGY SVPGIPASSG
     ATFGVDLGEQ LARDGVEVPK VVEKCAEAIE AYGLESMGIY RLSGTTSRVQ ALKNALDKDV
     DSVDVLSEEW SADINVVSGA LKLWFRELPE PLLTFGLYHQ FIEAARYEND RLRHIRLHEQ
     VNDLPDPNYA TLKFFMGHLD RVRRKDSINQ MSVSNLSIVF GPTLLGAPPN EGGLNLEHMS
     FQCKAIETIL EKYHEIFVEE EESAGTGAGT ATLEVS
//