ID A0A1Y2BR66_9FUNG Unreviewed; 447 AA.
AC A0A1Y2BR66;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:ORY37232.1};
GN ORFNames=BCR33DRAFT_789810 {ECO:0000313|EMBL:ORY37232.1};
OS Rhizoclosmatium globosum.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC Chytriomycetaceae; Rhizoclosmatium.
OX NCBI_TaxID=329046 {ECO:0000313|EMBL:ORY37232.1, ECO:0000313|Proteomes:UP000193642};
RN [1] {ECO:0000313|EMBL:ORY37232.1, ECO:0000313|Proteomes:UP000193642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL800 {ECO:0000313|EMBL:ORY37232.1,
RC ECO:0000313|Proteomes:UP000193642};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY37232.1}.
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DR EMBL; MCGO01000051; ORY37232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2BR66; -.
DR STRING; 329046.A0A1Y2BR66; -.
DR OrthoDB; 2184985at2759; -.
DR Proteomes; UP000193642; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000193642}.
FT DOMAIN 4..119
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 123..439
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 447 AA; 48533 MW; 776043D3CC554D4C CRC64;
MPSILLLGSG FVADPCLSYL LKRPENKITV AARRVANVTN LIAGRPNASA IALDVNDDAA
LEAAVAKHDV VISLIPYTHH ARVIKAAVKH RKHVVTTSYI SPAMMEYDQA AKDAGITVMN
EIGVDPGIDH LYAIKTIDEV HALGGKITSF TSYCGGLPAP ECSNNPLGYK FSWSSRGVLL
ALRNNAKCVQ DGKILDIPGP ELMNSAKPIP IYPAFAFEGY PNRDSTPYNE RYHIPEAKTV
IRGTLRYAGF PKFINALVKL GFLDDKEVPH VASTAAPIQW RALLSQAVGV NFTSVDALEA
AVRKTANLSG DDGERIIFGM KWLGMFSETN VHLRGTMLDT LCATLEDKMM YAPGERDMVM
LQHRFGVEYP NGKKEIRTST GLWFGVPNGD SAMATTVGVP CGIATQLILD GVLKRRGVIA
PMDAEINNPI LEALEKEGIF MVDEIIA
//
