ID A0A1Y2CPT9_9FUNG Unreviewed; 4013 AA.
AC A0A1Y2CPT9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Dynein heavy chain, cytosolic {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR33DRAFT_714104 {ECO:0000313|EMBL:ORY49032.1};
OS Rhizoclosmatium globosum.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC Chytriomycetaceae; Rhizoclosmatium.
OX NCBI_TaxID=329046 {ECO:0000313|EMBL:ORY49032.1, ECO:0000313|Proteomes:UP000193642};
RN [1] {ECO:0000313|EMBL:ORY49032.1, ECO:0000313|Proteomes:UP000193642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL800 {ECO:0000313|EMBL:ORY49032.1,
RC ECO:0000313|Proteomes:UP000193642};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY49032.1}.
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DR EMBL; MCGO01000010; ORY49032.1; -; Genomic_DNA.
DR STRING; 329046.A0A1Y2CPT9; -.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000193642; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46961:SF5; DYNEIN HEAVY CHAIN 6; 1.
DR Pfam; PF12774; AAA_6; 3.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000193642}.
FT DOMAIN 1015..1395
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1525..1606
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1607..1717
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1722..1776
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1909..2039
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2258..2335
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2402..2655
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2681..2971
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 3000..3201
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 3445..3558
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 3590..3710
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 3716..4006
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT REGION 96..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 766..793
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2856..2904
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3162..3189
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4013 AA; 456206 MW; 375C74CF8D0DC118 CRC64;
MSGPKRVPHL PLSFNPSNLV DRPQPLLENA QAVDISDPIA KSHAKRGVFS ELLTNPEESI
DDQLLISGQP PIIPPLEGLL GGTNLKAFPK AKTFYRPGFK RPHPGLNNTE RKRSVSMIGD
SSVSPRYGGS TMNMAGAGLA GSTINMAGST AMMTNVGGGD DNNLFQDGHG SGKRVRYNYS
KALEPKVLLP YESRPGQTPR KIEIERRKRL YANQSIEVLI ESALEEKLGD TPRDPLASKL
PLSAFDDVEY DQRTVKEWLD MSLPTLESLE AAKAAENNDK MAVIAADRVM KAAVPVPAKV
NLPSNNPAFD CLVTAYDSQE NLWKVRFIGF NGWELDNGGD YDMDENEDEN EDEYEDETER
LLACKTNEAW VERLKLLFLS EDPFLFAKRV ASAHKQREEV ALNLRYAFYL DCMPTAEASP
IPTTSLSKIC SIASGSNERL KKIALTATGK PLLDEVCLEY ARAMNKELFD HEVRAASNKD
TYSSVKLPSL PQPQKAPLTG CVEIAPYDYA KYAKDFSFVS FLTKLESIRT LSKVRVECDK
LLTNNLFLTS IAKIVKLDEF EGMQNQSLQN VKTQLKDGWI PTLKNIIKAG FKEVGKGWYN
MQESNSEKFM TTVNFIMQDS LRFLVLNSLV DFNKLISSIS SQRVVVTDTN DLIPPDNAKR
PLFQIDLTFK NGVISYNTDL GMYETAILNV FDKAMTAVES LPQLEPLVLD QMFWATKPNL
QIPHNKEPAI AKLREKLRRS LREGLGPLEE YLRTYDKHLR VLNLNINTYA EEYEEENHTI
EEMEQDIINH TKDWEALDKD IPSHISLGLF WVSCDSIRAA MRKDLAKVVL DILARRTAKI
AQGISQAFTG IQNRLKDHPT KIEELTELRD YMKTIPEECK NQNIKINEML RNYEILEKYK
YEQSNEDFRA RWTAYGWPMR IDEMVRATET SLEVDESTFL RNLASDQEVF KERIQNISGV
VADFSKNTDL SKLGEIVADV HKVTLELKEC QNLVTLFNSR ERLFNQEITH YEEVAQLIKD
FEPFKSLWLS VSDWSKWKNQ WLNGSFLDLN AEEVEKNLTN AWRVMFKSVK YFKNIPGCLA
VATQVKDEMD EFKPYLPLIQ ALRNPGMRDR HWDRLSEELN MKIRPDPTFT LNDALKMQLL
EKVEIITKVC DVAGKEYSIE AALDKMDNEW KSIALEILPY KETGTCIMKA AEEITRLLDD
HIVMTQSMSF SPFKKPFAER ISLWESKLRT VQEVLEAWMA CQRSWLYLEP IFASDDIVTQ
LPAESKRFTT MDRTWRRIMQ QAKAKPGVIE CCADFKLLDS FREFAFPRFF FLSDDELLQI
LSQTKDPTAV QPHLRKCFEN VAALEFQPDK LITGIFSGEG ERIDVADPFY PKGAVEEWLL
KVEDQMRKSV KKVIMAGLST YSSRPRTSWV LDYAGQAVIA VSQTFWTKEV SEALKTGQTG
LKTLFTRLLA QLQGLVSLVR GELPFLNRLV LGDLIVIDVH ARDVVKKLVD TGVCSENDFE
WISQLRYYWE DDDLRVKIVN ANFKYGYEYL GNTGRLVITP LTDRCYLTLT GAMHLGMGGA
PAGPAGTGKT ETTKDLAKAL AKHFFKGLAA AGAWACFDEF NRIDIETNAI MFEGVDLPLD
GSNAIFITMN PGYAGRTEPV AMMIPNYGMI GEISLFSFGF SNAKILAEKM VATFKLSSEQ
LSSQDHYDFG MRAVKTVISS AGNLKREQPN TIEDLIFCEH YLFPGVEQPP INYGDILDSL
NKTPEASFIK KCIQLYETTV VRHGLMLVGP TGGGKTCCTR VLSRALSALQ DIEKVRVHVL
NPKSITMGQI YEGIDDGLPD KKWYCFDGPV DAVWVESMNT LLDDNKKLCL SSGEIIKMAN
TQTMMFEVEN LQYASPATVS RCGMIYMEPG ALGRSLPPSY ISIFRSIVDP LFEHYLEPAL
KFLRGNIREA VGTTDGNLTI SMMRILQCLM MPFVATDDPN APNPAERINF FGEILESLFL
FSIVWSIGAT SDADGHKKFE GWLRGMMSEK PPKIPFPENG SIYDYMFDQE RKEWANWMEY
APEFVVPQKG SSQDVIVPTM DTIRNTYILH ILLHNGCHTL CTGPTGTGKS VTITDKLMKG
MDSTFTPLIF SFSARTGANQ TQDLIDSKME KRRKGVFGPP VGKKFVIFVD DLNMPMLDNL
CGAQPPIELL RQWLDYGGWY DRKAVGKFME LVDLTFVCGM GPPGGGRNPI TQRMTRHFNL
LSFVEMEDES LQRIFSTILG SFLQKFPPEI SSKTDAIVSA SVHIYNTIRA ELLPTPAKSH
YTFNLRDLAK VVQGVLSADI KTVNIETDIV RLWIHECMRV FQDRLVDNVD KTWFLELVKG
TIEEKLILTW QDVVLNEPII YGDYLTPGAD PKIYTEVKDI RRLVKLAEEY LDDYNSTTTS
PMRLVMFLDA IEHVSRICRI IRAPMGHALL LGVGGSGRQS LSRLATYMEE YEMFQIEISK
NYGTTEWRDD LKKVLMWAGM DAKQVVFLFC DTQIFQEACL EDINNILNGG DVPNIYANDE
IDQILNAMRP IALDMGITAN RENLFALYIQ RVRNNLHLII CMSPIGDAFR NRLRMFPSLV
NCCTIDWFST WPEEALRSVA ANSISEVSDL GSEQVIDGIV NLCMYMHESV RACCLKYKNE
VNRNNYVTPK SYLELEILQE ELEAMAPMLL QTSQETEFAM KKIAVDKVKA EEMKEIVMKE
EASATKKAEE TKNIAEDAKR IWTKLFQLWL QLLIRSMQRP PEGVKLVIEA ICIMKGIKPK
KIDGDKPGKK IDDYWEPGKG LLAEPQKFLD SLMNFDKDNI QEAVVTKIKP YIDSQEFQVS
VIARVSKAAT SMCQWVRAME KYYWVSRSVA PKRAVLQAAQ ESLEITLKTV AELKKKMREA
EINIKEMEKR YTESVAKKEE LSRKVEECNV KLSRAGKLIS GLGGEKQRWA LTVSQLDQKI
TNVVGDVLLA SGVIAYLGPF TAEYRSDLLR EWNNNLLRLK IPHSDVISLW DSLGDPVKLR
EWELAGLPRD SLSRDNGIIV QNSRRWPLLI DPQGQANKWI RNMEKDNQLD IVKLTDKDFL
RTLENAIRFG KPVLLENVGE KLDPALDPVL LRMTFKQGGN VVIKIGDSIL PYHEDFRFYI
TTKLPNPHYS PETSATVTLI NFTLAPSGLE DQLLAIVVAN ERPDLEEAKN QLTINNAQMK
KELKDIEDKI LYLLSSVQGS PETSEEITSK VIIAEQTEKD IDYTRNKYVP VAVRTRILFF
CITELATIDP MYQYSLGWFM NLFISAISHS EKSENIEQRI VNINEYFTFS LFSNVCRSLF
EKHKLLFSFL LCIRMMMNDD KIDMDEWKFL LTGAAPPGVE KKLPNPAPDC LALSQLPAFE
NFELDFVDFI ESYRVIFDSQ IPHREKLPHK WQNGITPFQR ILVLRCIRAD RCTSAVQDFV
ASQLGDRFVE PQTSDLGAVY KESSAVIPLI FVLCPGADPA NSLYKFAEEM RFSKKLTGVS
LGQGQGPKAE ALIREGLERG LWILLQNCHL APSWMPTLDR IIDGVTPDKV HRDFRLWLTS
LPTPKFPVTI LQNGVKMTVE PPNGIKANLM RTYSTFTDDY LSQCTKPREW KKLLFALSFF
HAVIQERRKF GALGWNIPYE FTDGDLRICI RQLKMFLEEY TEIPFKVLKY TVGKSTTDYY
TPRSIDDGYK FSTSEIYVSI PPENLSAYKN YIKSLPIDEV TEIFSMHENA NITFAQKETY
TMFEILLNLM PRSTKNAGGK TRDEILAETA ISIQSRIPKP YSMAMVTAKY PIEYKESMST
VLIQEVIRYN RLLSVIHQTI VELLKALKGL VIFINQVPAA WAAKAYPSLK SLSTWVIDLM
ARTDFIQKWI DNGIPVVFWI SGFFFPQAFL TGTLQNFARK YTISIDTLQF DFKMVDNRWE
DIHTKPSDGC YIRGLYLEGA RWDPTRRVLA ESRPKELYTE MCVIWLLPKA NRKKPESGIY
ECPVYKTLTR AGTLSTTGHS TNYVLTMELP SDKLMSHWVK RGVALITSLG SGW
//
