ID   A0A1Y2CSK1_9FUNG        Unreviewed;       864 AA.
AC   A0A1Y2CSK1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=TNase-like domain-containing protein {ECO:0000259|PROSITE:PS50830};
GN   ORFNames=BCR33DRAFT_713576 {ECO:0000313|EMBL:ORY49982.1};
OS   Rhizoclosmatium globosum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC   Chytriomycetaceae; Rhizoclosmatium.
OX   NCBI_TaxID=329046 {ECO:0000313|EMBL:ORY49982.1, ECO:0000313|Proteomes:UP000193642};
RN   [1] {ECO:0000313|EMBL:ORY49982.1, ECO:0000313|Proteomes:UP000193642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEL800 {ECO:0000313|EMBL:ORY49982.1,
RC   ECO:0000313|Proteomes:UP000193642};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY49982.1}.
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DR   EMBL; MCGO01000008; ORY49982.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2CSK1; -.
DR   STRING; 329046.A0A1Y2CSK1; -.
DR   OrthoDB; 375531at2759; -.
DR   Proteomes; UP000193642; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 2.40.50.90; -; 4.
DR   InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR   InterPro; IPR002999; Tudor.
DR   PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR   PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00565; SNase; 3.
DR   Pfam; PF00567; TUDOR; 1.
DR   PIRSF; PIRSF017179; RISC-Tudor-SN; 2.
DR   SMART; SM00318; SNc; 3.
DR   SUPFAM; SSF50199; Staphylococcal nuclease; 4.
DR   PROSITE; PS50830; TNASE_3; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193642};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          8..154
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          182..322
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          459..621
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
SQ   SEQUENCE   864 AA;  92739 MW;  3718C2EF418C56DE CRC64;
     MTTNSLPSSG RAIVKSVMSG DGVVLRGRPV NGPPPERILS FSNVVAPRLG TASDPSKEET
     GAFESREFLR KLLIGKEVSF KVEYTTTTNN RDFGSLTLAA PGVDGETNVS RLLVKHGWVK
     VKSAEGKRAP TDEHAVLLGL EAAAQAGGLG VWNSKLTPRN VSFTTADSRE FLDAHKGKPI
     QVQQTAIVDQ IRDANTIRVV IVVPDSSNPS KLIHQYININ LTGIKAPVYR AGVPNLEDII
     EPFSQEAKFF VESRLLQRDV NVVLEGVNTN GVFIASLIHK VGGSIAEALL AEGYASVVSW
     QVGMLKAAEA LAKEKKLRIW KSFVSKASTP VAGGKDAGLQ TLMPSIFVVP VSKPDAAERR
     IWFASLRAPP KAPGETTESG YGHEAKEVFP PSKAYGKTVH VNLDFIKPKE NEFDERFYKA
     LKALKGLHSG KEAPVIRFVD ASESASKAKS FLSALQRNKT VAGVVEFASS GSRFRVWIPS
     QNIKITLVLS GVRTPKAARA NGTAKAAPAE KAEPFGNEAL DLANRRALQR DVEVSVEGID
     KAGGFIGSLY IPLSGAGSTG AATSIPGAGA RASSTENFAI LLLDAGFATI HDYSASQSPQ
     ASQLYAAEKR AQDKRAGIWS IRDPLEEARA KEEASAAANG ESDFKDTTQE VYVSEIGNGG
     EIHIQTVGPD LARLEKVMAE FALFYKTPQP ALAIPPKVNE IVAAKFTADD QWYRARIREV
     QPETKTFPLT RIRALAPQFS TTVLPAQSRE SRLAFLTVPK IGEEGGDAAY DRLRDDMEAR
     KLIARVLTGG RPSDPLQVVL SVPAGADGKG GECLNLSFVA DGVASCGATK EFEEGGLAAL
     ITAQDAARKS RLGIWRYGDF RDDD
//