ID   A0A1Y2CWZ8_9FUNG        Unreviewed;       786 AA.
AC   A0A1Y2CWZ8;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=DNA ligase/mRNA capping enzyme {ECO:0000313|EMBL:ORY50865.1};
GN   ORFNames=BCR33DRAFT_734052 {ECO:0000313|EMBL:ORY50865.1};
OS   Rhizoclosmatium globosum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC   Chytriomycetaceae; Rhizoclosmatium.
OX   NCBI_TaxID=329046 {ECO:0000313|EMBL:ORY50865.1, ECO:0000313|Proteomes:UP000193642};
RN   [1] {ECO:0000313|EMBL:ORY50865.1, ECO:0000313|Proteomes:UP000193642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEL800 {ECO:0000313|EMBL:ORY50865.1,
RC   ECO:0000313|Proteomes:UP000193642};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|ARBA:ARBA00007572}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY50865.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MCGO01000006; ORY50865.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2CWZ8; -.
DR   STRING; 329046.A0A1Y2CWZ8; -.
DR   OrthoDB; 2788069at2759; -.
DR   Proteomes; UP000193642; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR   PANTHER; PTHR45997:SF1; DNA LIGASE 4; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ORY50865.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193642};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..786
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012192296"
FT   DOMAIN          415..556
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   786 AA;  88113 MW;  07A16FF0F8576D79 CRC64;
     MYVIWMLIAN VVGVVQSANT LYNQSVSGAT RTDARDLGLR RQIETELRQL TRTVTGDTAS
     ETASELLPLV RVLAPALERE RVFGLKANGL RRLLLASNAL GTKSAPTAAA LLNCDNSDST
     AFATAVFRCL EYLPTRPSLP LTISRLDSLL HELASFSGFS VDEFGVQLKK SQRVQQQVIS
     DLFRGRTALE ARFITQVILK VPVSPFHESW ALAIFHPSFW RIYKFQPNLR AACRAIELER
     SASALKEING NQRQHQPTQL QVGVNLANMA LTKATSCAHV IRHMQSQGET EFVAEVKYDG
     ERNQIHFNAN ATDHEKRITL YSKSKRNSTS DRILCHDIVL ATLGIKESNQ PNIKPTLDSS
     KQYTPVTSAI FDSEILVFNE STQSVEPFHE ARAFASEKSR STNHDILTTQ KHYLLVFFDI
     MYLNGESLLS LPYVQRREIL EQVIRPIPNY SAVSETRRFQ LQLDPDEACT QLRKYFLQVC
     ARPAEGLVCK GVSGRYEPGR DSLWMKLKKD YIAGFGDTAD FVVLGGSYRH DLTDYLGITR
     KDDSGLLNIY FVGAQLNRGV QGEPPHYVIL FDFCAGFSRD SLLFFSKSTT PIRHPTPKTL
     SYTLHQSTPT SKIESFFDPP LTVELKGGGF ENRNGRWALR GPRYIRTCGP DRGWWDAVTY
     QEFSAMAVKS TKPSQWDLEY DKLAAVDAQV SAKLVRKRSS TLSSVGSRRS SFSCGMGKRR
     MSEVSSVGQA VPVVVDDLFD IAELVYWQNP SLASIRRENV SSALMYIPGT RNAGIAETTW
     YNQCAR
//