ID   A0A1Y2D034_9FUNG        Unreviewed;       410 AA.
AC   A0A1Y2D034;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=BCR33DRAFT_712160 {ECO:0000313|EMBL:ORY51955.1};
OS   Rhizoclosmatium globosum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC   Chytriomycetaceae; Rhizoclosmatium.
OX   NCBI_TaxID=329046 {ECO:0000313|EMBL:ORY51955.1, ECO:0000313|Proteomes:UP000193642};
RN   [1] {ECO:0000313|EMBL:ORY51955.1, ECO:0000313|Proteomes:UP000193642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEL800 {ECO:0000313|EMBL:ORY51955.1,
RC   ECO:0000313|Proteomes:UP000193642};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY51955.1}.
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DR   EMBL; MCGO01000004; ORY51955.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2D034; -.
DR   STRING; 329046.A0A1Y2D034; -.
DR   OrthoDB; 20281at2759; -.
DR   Proteomes; UP000193642; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:ORY51955.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193642}.
FT   DOMAIN          11..381
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   410 AA;  46495 MW;  4CA1F06996D17BA6 CRC64;
     MYSDDFLKRI PKTDLHCHLD GSIRLSTLID LAQEQGVTLP SYTVDGLKDL VFKPAYNNLE
     EYLECFAYTT AVLRNAKALE RVAYELAVDQ FDIGCRYFEV RFAPQLNAIP GELSIEQVIL
     AVNDGLQRAI KEYNAKPEVA SGDEPEYCAG IVLCAMRMFT ADMSPYYKNF WEVHQHETAK
     RIYGLASVAL VATAGKLRDA VDVPIVALDI AGAEAGFPAS DHKEAFELAH KKFFFKTVHA
     GEGYGPESIF QAITDCHAER IGHGFHLFNT DHFSNPNRTM ESRQLYINRL IQYMATMRIC
     IEVCVTSNLQ TIPGTTLADH PIKRMLDNKM AITLCSDNTT VSSTDVLKEL KMTVDAFQLT
     PQQLKDISIT GFKRSFMHKD YVLKRRYVRK VIDFYERLER EYWINASSSS
//