ID   A0A1Y2D1P1_9FUNG        Unreviewed;       422 AA.
AC   A0A1Y2D1P1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN   ORFNames=BCR33DRAFT_189420 {ECO:0000313|EMBL:ORY53170.1};
OS   Rhizoclosmatium globosum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC   Chytriomycetaceae; Rhizoclosmatium.
OX   NCBI_TaxID=329046 {ECO:0000313|EMBL:ORY53170.1, ECO:0000313|Proteomes:UP000193642};
RN   [1] {ECO:0000313|EMBL:ORY53170.1, ECO:0000313|Proteomes:UP000193642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEL800 {ECO:0000313|EMBL:ORY53170.1,
RC   ECO:0000313|Proteomes:UP000193642};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY53170.1}.
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DR   EMBL; MCGO01000002; ORY53170.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2D1P1; -.
DR   Proteomes; UP000193642; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193642};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        112..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          210..300
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   422 AA;  48165 MW;  A7AB389F2125BAC2 CRC64;
     MPSEQENFFT LLDLLPPKHG GKQTDLDPYF GIKAYTKAAF DPYAAPETQE KLLECSELPL
     FDYQPEKIWG LCRTVKADWK LLWRPHQHYE LGNCLIFESQ SRKHKLGTYH LLSNYINAVE
     AVVLSLFVLT NLISWYKNYM TSTGYVYLAA YLGKAEDTNG YWHTTSIFLG PGTLIMSIIV
     LAWALTRNER TPCGLLRYLR QIGKPLVEEV MFSYSWQPGI QNDIRCLARG ILKNEIGVWI
     DVLKLISGDK ASRVTRTVAA HARFVVVCLT AAYVNSPACF IELYEALNAP VSAKDRVIVF
     WPDEAKMGLS YKEEDMKRVT ALAGQLEKKG ITVIREYSRL IDYLNHRVIY SVDLSHYIWW
     LKHVGSGFGV PDKAILPTVS KLKRFNLFGK FAPKNAVTIS NLWLSSDMRK TTEKGYAFHF
     SS
//