ID A0A1Y2DN61_9PEZI Unreviewed; 1266 AA.
AC A0A1Y2DN61;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Oxysterol-binding protein-domain-containing protein {ECO:0000313|EMBL:ORY60594.1};
GN ORFNames=BCR38DRAFT_459641 {ECO:0000313|EMBL:ORY60594.1};
OS Pseudomassariella vexata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Pseudomassariaceae; Pseudomassariella.
OX NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY60594.1, ECO:0000313|Proteomes:UP000193689};
RN [1] {ECO:0000313|EMBL:ORY60594.1, ECO:0000313|Proteomes:UP000193689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY60594.1,
RC ECO:0000313|Proteomes:UP000193689};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000256|ARBA:ARBA00008842,
CC ECO:0000256|RuleBase:RU003844}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY60594.1}.
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DR EMBL; MCFJ01000011; ORY60594.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2DN61; -.
DR STRING; 1141098.A0A1Y2DN61; -.
DR InParanoid; A0A1Y2DN61; -.
DR OrthoDB; 960at2759; -.
DR Proteomes; UP000193689; Unassembled WGS sequence.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13292; PH_Osh1p_Osh2p_yeast; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR018494; Oxysterol-bd_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF205; OXYSTEROL-BINDING PROTEIN; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS01013; OSBP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000193689};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REPEAT 191..213
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 298..330
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 388..483
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..563
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..602
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1266 AA; 140300 MW; 9F189D07D1564ECE CRC64;
MPDTGDSSQH KRSRSSAALS LLRRKDKDVR HDDNSPSEDV VSHATLGLTS RPTTAQSPTS
IPVHQQSVKG HNSRMSLGRV SSQPAANPQA VSRASLNIGD RGATTIEQSV RKFRIVEALR
SGNTAAISKA IRETSENPTR ISTSSINATN IAPLEDTTVL HLAIQCAEFD VVEYVMSDGA
GYIDVNARDK DGNVPLHIAA AQGRGPIVRL LLEQKDINDA IANNQGKLPL DVARNPDIFQ
QLQLSRTLFV QDKVKHVQDL VRRQDYDTLG QVLEEPRVKT ILDINSNELP SDIITVQAGG
TLLHEAARRK DTKLIQALLL HGADPFQRDR RGKLPQDVTK DDLTRAMLKK SPAAVAAQRG
IQEKAVLGHA ASQGGAVPTA ADPLGGREQT MKGYLKKWTN YRKGYQLRWF VLENGVLSYY
KHQDDAENAC RGAISMRIAK LNMSPDEKTK FEIIGKSSVK YTLKANHEVE AKRWFWALNN
AIQWMKDQAK EEQKQKAQTA EYLRQAKDQL TSKSAEASIN DPSEAASVGE ARSSVQLSRF
PSTKLSTSRT GLSHASTTGS IDDEFAETGG ADDLSRAHSN GAPTVPGDDN DDDDEDDDEE
SSGGERPTAT KDAFNITAQS AKLQLDTLAQ VSAALQAEAN RNPGMSMADP KAAQALATYD
AAIKSLKGLM GDLLRISKDR DAHWQYRLDQ EIEMRQMWEE SMAKVAKEQE ILEARIGEAE
HKRKITKRAL REVMESSHDG GRPGSSYSAA PAVPAVPAES TGVTEEEVTE GRKSPSTKSI
LRRPTALSQV VDISEDSESE QEEFFDAVDA GEVDVEELPP SESANLGNAE QAVVVSGGLD
VSSTYKGYEN GVRTRLKLDS DNRPKVGLWG ILKSMIGKDM TKMTLPVSFN EPTSLLYRTG
EDMEYADLLD LAADRSDSIE RLLYVAAFAA SEFASTIGRV AKPFNPLLGE TFEYARPDKG
YRFFIEQVSH HPPIGAAFAE SAKWTYYGEA NVKSKFLGRT FDIQHLGTWF LELRPTNGGK
PDFYTWKKPT SCVVGIITGN PAVDNYGPME IKNWTTGEEC KLEFKPRGWK ASSAYHLNGK
IMDSDGRPRF SLGGRWNSKL YARYTPGYEA TVEEPTDGGS ILRGSISDSQ KAFLLWQAHE
RPEGIPFNLT PFVLTFNHLD ENLRQWIAPT DSRYRPDQRA MEDGEYDTAA AEKDRLENDQ
RKRRRVREEH GEHFTPAWFE KAKCPTTGEE YWKFTGKYWE QREKYGSGDQ HAWDGLEPLF
VPQQDS
//
